Houston is coming into this game with a 14-0 record this season but they are only playing their 2nd road game of the season here. They are coming off of a huge win at home against West Virginia in their last game but now they are going on the road to play their 1st conference road game of the season and this will also be their 1st conference road game as a Big 12 team. They have been playing very well in their recent games but they have definitely struggled more on the road as their only road game this season was a 6 point win against a 7-7 Xavier team. They also played a much closer game in their last game at a neutral location, only beating Texas A&M by 4 points. They are going up against an Iowa State team that is 11-3 this season and has been playing very well in their recent games. They have won 6 of their last 7 games with all 6 of those wins coming at home and by 10+ points. They are coming off of a loss in their last game against Oklahoma but that was an 8 point loss on the road against an Oklahoma team that is ranked number 11 in the country. That was also their 1st conference game of the season so they are 0-1 in the Big 12 now but they are going to be hungry to bounce back here at home and get their 1st conference win. They still played very well in that game against Oklahoma and they have been much better at home all season, they are going to get up at home for this Big 12 newcomer and they will be extra motivated to give Houston their 1st loss of the season. Iowa State will cover the spread in this game.