Jared Goff will struggle to drive the football down the field vs. the Niners' defense. He will be cautious, forcing Detroit into a conservative offensive game plan to wear down the Niners' below-average run defense. While this may be the best course of action in a vacuum, I don't envision it leading to big chunk plays or opening up the passing game via play-action on the road in a conference championship atmosphere.

As talented as the 49ers' offense can be, there's no denying the impact a limited or unavailable Deebo Samuel will have on their game plan. I predict the home team will manage to get out to a sizable first-half lead with the Lions unable to create scoring opportunities, prompting the Niners to lean on their ground game in the second half. This slow-paced attack — they run the slowest-tempo offense in terms of seconds per play — will work in the under's favor one way or another. If it's successful, it will drain the game clock, but if Detroit's talented run-stop unit rises to the occasion, these teams will end up punting the ball back and forth until the final whistle blows.