The Saints won big at home on Sunday, defeating the Packers by a score of 44-23. They have to head out on the road just a few days later, and I don't like their chances against a Carolina team that is hungry for a win. The Saints are 0-4 on the road so far this season, and I think they'll make it five straight tonight.

Here are my keys to the game:

1. Saints Defense - New Orleans ranks near dead last in the NFL against the pass, allowing an average of 289 yards per game.

2. Previous History - The Panthers have won three of the last four meetings, scoring an average of 32 points during those victories.

3. X-Factor - The home team has won five of the last six in this series.

Selection: This is a play on the Carolina Panthers (10*)