Total: 49.00 | -107.00 Under
The Colts come into Arizona without their entire starting offensive line, so we can expect the offense to stall here in this Christmas day game. The Cardinals are coming off back to back losses, and their offense has struggled in those games. Kyler Murray has thrown three picks and just one TD pass in his last two starts. He hasn't looked the same since returning from an injury, and the loss of DeAndre Hopkins isn't going to help. The under is 6-1 in the Cardinals last seven games following an ATS loss.