The Chicago White Sox are coming off back-to-back losses to the Rangers in Texas, but they look good in Game 1 of a new series in the Bronx. The Yankees are struggling, sitting dead last in the AL East, and they will have to face Chicago's ace tonight.

Here are my keys to the game:

1. Pitching - Chris Sale will be on the mound for the Sox, and he's been flawless so far in 2016. Sale (7-0, 1.79 ERA) gave up a pair of runs on three hits, striking out nine in seven innings in a win over the Twins in his last outing. He's 2-1 with a 1.34 ERA in his last five starts versus the Yankees.

2. Batter vs. Pitcher - Chicago's slugger Jose Abreu is having himself a fine season, batting .252 with five home runs and 22 RBIs. He was 2-for-4 in the series finale at Texas, and he's 2-for-3 lifetime versus Luis Severino.

3. X-Factor - Injuries have taken their toll on the Yankees, with Mark Teixeira missing the last two games with neck spasms, and Jacoby Ellsbury missing the last five games with a hip injury. Alex Rodriguez is on the DL with a hamstring injury.

Selection: This is a play on the Chicago White Sox (8*)