MIKE'S CFB GAME OF THE WEEK - IOWA VS IOWA STATE TOP PLAY
(NCAAF) Iowa vs. Iowa State, 09/11/2021 4:30 PM, Score: 27 - 17
Point Spread: -4.00 | -110.00 Iowa State (Home)
Result: Loss
No. 10 Iowa opened the season with a dominant 34-6 win as a 3.5-point favorite against Indiana while No. 9 Iowa State just barely beat Northern Iowa as a four-touchdown favorite.

Those results are working in our favor here as we're getting Iowa State at a good number while putting Iowa in a potential letdown spot. There's just no way the Cyclones are coming out as flat here in this big-time rivalry game, so let's take advantage as the bookmakers and the public overreact to last week's results.

Hawkeyes are 1-7 ATS in their last 8 games as a road underdog. Cyclones are 4-0 ATS in their last 4 games following an ATS loss. The home team is 4-0 ATS in their last 4 meetings.

10* play on Iowa State.