San Diego at Houston 7:10 ET
Padres over Astros- The Astros (80-62) seized sole possession of first place in the American League West for the first time this season with their dismantling of the Rangers. But Friday the Astros absorbed an 11-2 beating in the opener of a three-game interleague series vs. San Diego. It marked the Astros' sixth consecutive home loss and their 10th over the last 12 games at Minute Maid Park. Right-hander Cristian Javier (9-3, 4.65 ERA) has the starting assignment for the Astros on Saturday while . Right-hander Seth Lugo (6-6, 3.49) is the scheduled starter for the Padres and he is unbeaten in his last five starts with a 1.24 ERA. Take SAN DIEGO!