Pittsburgh at San Francisco 10:15 ET
Giants over Pirates- Two pitchers that appear headed in opposite directions will face each other tonight in San Francisco as the Giants send Matt Cain (8-8, 4.35 ERA) to the hill to oppose the Pirates Jeff Locke (9-4, 2.90). Locke is winless over his last five starts and surrendered eight runs in 2 2/3 innings his last time out against Arizona while Cain has turned his season around going 3-2 with a 2.41 ERA in his last six starts. He is 3-2 with a 2.79 ERA in 10 starts against Pittsburgh. Take GIANTS!