The Cardinals have the nation's top-rated offense and they're facing a Seminoles defense that will be without preseason All-American defensive back Derwin James, who tore knee cartilage during last week's blowout of Charleston Southern. Last week Louisville just completely destroyed Syracuse inside the Carrier Dome in a 62-28 final. Quarterback Lamar Jackson accounted for 5 touchdowns as the Cardinals offense posted over 600 yards of total offense. Surprisingly 4 of Jackson's touchdowns came on the ground as he rushed for 199 yards on 21 carries. After two straight weeks of huge performances, Jackson has started catching some national attention. The Cardinals quarterback has posted Heisman Trophy type numbers in his first two games of the season with 697 yards, 7 touchdowns, and 1 pick through the air along with another 318 yards with 6 touchdowns on the ground. I think the X-factor will be explosive QB Lamar Jackson. I like the Cardinals here at home to get a big win.