The Rams made this trip last season, and I like the familiarity aspect they have with this trip. I also give an edge on the team's decision to remain in Jacksonville following last week's game before crossing the pond. Lastly, this Cardinals defense that's given up the most passing TD's of 20+ yards will meet L.A.'s top ranked scoring offense that leads the league in scoring and 20+ yard plays. Arizona is the only team that's allowed 100 QB pressures – Carson Palmer has been hit an NFL high 55 times and the Rams defense, led by Aaron Donald is averaging 13 QB pressures per game. There might not be a more disruptive defender in the entire NFL than Aaron Donald. That guy is pretty much unstoppable at this point, and Palmer under pressure is very vulnerable to making mistakes. Take L.A. Rams in this one.