2026 MLB Betting Trends: Best Run Line, Moneyline, and Totals Picks by Team

By: Alex MacMillan Updated 09/09/2026, 03:54 AM ET

The 2026 MLB season has produced clear separation in the betting market, and the team-by-team numbers tell the story. The Tampa Bay Rays have been the most profitable club to back on the run line, while the Seattle Mariners and Los Angeles Angels have been steady money-losers no matter the side. Below are the full 30-team rankings for every major market, sorted by return on investment, to sharpen your best bets and build smarter parlays.

Records reflect flat 1-unit stakes at the closing line through September 8, 2026. A positive ROI means blindly backing that side all season would have shown a profit.

Four angles stand out across the full board this season: Tampa Bay on the run line (75-65, plus 12.0 percent), Washington on the first-5 run line (90-55, plus 16.5 percent), the Angels on team-total Unders (plus 13.3 percent), and Minnesota on full-game Overs (77-57, plus 8.4 percent). Each is anchored by a large sample, which is what separates a genuine market edge from a hot streak.

Run Line Picks (Against the Spread)

The run line applies a 1.5-run spread to every game. Tampa Bay leads the league at 75-65, with Milwaukee and Atlanta close behind. On the other end, Seattle has been baseball's worst run-line team this season.

Rank Team ATS Record Units ROI
1 Tampa Bay Rays 75-65 +20.35u +12.0%
2 Milwaukee Brewers 75-69 +16.00u +9.7%
3 Atlanta Braves 73-69 +12.85u +7.8%
4 San Diego Padres 78-62 +12.20u +6.5%
5 Washington Nationals 82-61 +8.65u +4.4%
6 New York Yankees 70-72 +6.30u +3.9%
7 Chicago White Sox 81-59 +7.75u +3.8%
8 St. Louis Cardinals 79-62 +2.35u +1.2%
9 Boston Red Sox 69-71 +0.60u +0.3%
10 Arizona Diamondbacks 76-64 +0.55u +0.3%
11 Houston Astros 74-70 -0.05u -0.0%
12 Colorado Rockies 77-66 -1.80u -1.0%
13 Chicago Cubs 68-74 -2.25u -1.3%
14 Toronto Blue Jays 73-70 -3.15u -1.7%
15 Baltimore Orioles 73-70 -3.30u -1.7%
16 Miami Marlins 73-69 -5.60u -2.9%
17 Minnesota Twins 76-66 -7.00u -3.5%
18 Detroit Tigers 67-71 -7.20u -4.0%
19 Cincinnati Reds 74-67 -10.80u -5.4%
20 Kansas City Royals 70-69 -15.70u -7.9%
21 Pittsburgh Pirates 66-74 -14.55u -8.0%
22 Cleveland Guardians 66-77 -16.45u -9.0%
23 New York Mets 64-77 -16.45u -9.2%
24 San Francisco Giants 70-72 -20.30u -10.2%
25 Los Angeles Angels 70-72 -23.60u -12.0%
26 Texas Rangers 63-77 -22.30u -12.0%
27 Athletics 68-76 -24.95u -13.0%
28 Philadelphia Phillies 60-82 -27.50u -16.4%
29 Los Angeles Dodgers 59-83 -29.95u -17.8%
30 Seattle Mariners 55-88 -31.00u -18.4%

Moneyline Picks (Straight Up)

Moneyline ROI rewards teams the market has underrated, not just the ones that win most. The Chicago White Sox top the board at 75-68 because so many of those wins came at plus money, with Tampa Bay second and Atlanta third. The Angels have been the single biggest moneyline drain in the sport.

Rank Team Record Units ROI
1 Chicago White Sox 75-68 +13.65u +8.8%
2 Tampa Bay Rays 85-58 +14.15u +7.7%
3 Atlanta Braves 85-58 +10.60u +5.4%
4 Milwaukee Brewers 88-56 +11.25u +5.3%
5 Arizona Diamondbacks 76-68 +8.60u +5.1%
6 St. Louis Cardinals 72-72 +7.05u +4.5%
7 San Diego Padres 75-68 +1.20u +0.7%
8 Miami Marlins 72-72 +0.45u +0.3%
9 Chicago Cubs 81-63 +0.30u +0.1%
10 Philadelphia Phillies 80-63 -1.40u -0.7%
11 Washington Nationals 67-78 -1.25u -0.8%
12 Boston Red Sox 79-65 -2.05u -1.1%
13 Cincinnati Reds 69-74 -2.80u -1.8%
14 New York Yankees 81-62 -5.95u -2.9%
15 Cleveland Guardians 73-71 -6.55u -3.6%
16 Minnesota Twins 68-75 -6.75u -4.2%
17 Toronto Blue Jays 72-72 -7.55u -4.3%
18 Houston Astros 73-71 -7.85u -4.5%
19 Colorado Rockies 55-88 -8.05u -5.6%
20 Texas Rangers 71-73 -11.10u -6.4%
21 Los Angeles Dodgers 86-57 -19.65u -7.1%
22 Baltimore Orioles 69-75 -12.30u -7.3%
23 Pittsburgh Pirates 71-73 -13.35u -7.5%
24 Kansas City Royals 64-80 -15.90u -9.9%
25 San Francisco Giants 59-85 -21.35u -13.4%
26 Detroit Tigers 65-78 -24.20u -13.8%
27 Athletics 57-87 -23.80u -15.0%
28 New York Mets 65-78 -26.80u -15.2%
29 Seattle Mariners 67-77 -30.20u -15.7%
30 Los Angeles Angels 54-89 -25.50u -16.8%

Full-Game Totals Picks (Over / Under)

Totals splits cut both ways, so we rank the Over and the Under separately. The Minnesota Twins and Chicago White Sox have been the league's premier Over teams, while the Los Angeles Angels and Arizona anchor the Under side.

Best Over Plays

Rank Team Over Record (O-U) ROI
1 Minnesota Twins 77-57 +8.4%
2 Chicago White Sox 80-61 +8.2%
3 Chicago Cubs 80-62 +7.9%
4 Washington Nationals 75-62 +4.7%
5 Seattle Mariners 75-62 +4.4%
6 Cincinnati Reds 76-65 +2.7%
7 Texas Rangers 73-63 +2.6%
8 Pittsburgh Pirates 74-64 +2.4%
9 Athletics 73-66 +0.6%
10 Houston Astros 71-64 -0.2%
11 Toronto Blue Jays 71-69 -2.9%
12 Miami Marlins 71-69 -3.2%
13 San Francisco Giants 66-65 -3.5%
14 Baltimore Orioles 70-70 -4.3%
15 New York Mets 63-67 -7.3%
16 Boston Red Sox 68-72 -7.5%
17 Tampa Bay Rays 66-71 -7.5%
18 Colorado Rockies 68-72 -7.5%
19 Kansas City Royals 66-73 -8.8%
20 Philadelphia Phillies 64-71 -8.8%
21 St. Louis Cardinals 65-72 -9.1%
22 Atlanta Braves 64-72 -9.7%
23 Cleveland Guardians 67-76 -9.9%
24 Los Angeles Dodgers 66-75 -10.6%
25 Milwaukee Brewers 64-76 -12.1%
26 San Diego Padres 62-76 -13.7%
27 Detroit Tigers 61-76 -14.2%
28 Arizona Diamondbacks 61-77 -15.0%
29 New York Yankees 61-77 -15.3%
30 Los Angeles Angels 58-82 -20.1%

Best Under Plays

Rank Team Under Record (O-U) ROI
1 Los Angeles Angels 58-82 +11.8%
2 Arizona Diamondbacks 61-77 +6.5%
3 New York Yankees 61-77 +6.5%
4 Detroit Tigers 61-76 +6.0%
5 San Diego Padres 62-76 +5.2%
6 Milwaukee Brewers 64-76 +3.7%
7 Atlanta Braves 64-72 +1.8%
8 Los Angeles Dodgers 66-75 +1.7%
9 Cleveland Guardians 67-76 +0.8%
10 Philadelphia Phillies 64-71 +0.7%
11 Kansas City Royals 66-73 +0.7%
12 St. Louis Cardinals 65-72 +0.2%
13 Colorado Rockies 68-72 -1.1%
14 Tampa Bay Rays 66-71 -1.3%
15 New York Mets 63-67 -1.6%
16 Boston Red Sox 68-72 -1.7%
17 Baltimore Orioles 70-70 -4.0%
18 San Francisco Giants 66-65 -4.7%
19 Miami Marlins 71-69 -5.5%
20 Toronto Blue Jays 71-69 -5.6%
21 Athletics 73-66 -8.7%
22 Houston Astros 71-64 -8.9%
23 Texas Rangers 73-63 -10.4%
24 Pittsburgh Pirates 74-64 -10.8%
25 Cincinnati Reds 76-65 -11.6%
26 Washington Nationals 75-62 -12.6%
27 Seattle Mariners 75-62 -12.7%
28 Chicago Cubs 80-62 -16.0%
29 Chicago White Sox 80-61 -17.3%
30 Minnesota Twins 77-57 -17.7%

Team Total Picks (Over / Under)

Team totals isolate one club's run production rather than the combined score. The Chicago Cubs and Washington have cleared their team numbers more than any other lineups, while the Angels and Mets have been the most dependable team-total Under sides.

Best Team-Total Over Plays

Rank Team Over Record (O-U) ROI
1 Chicago Cubs 82-62 +6.2%
2 Washington Nationals 80-65 +4.2%
3 Minnesota Twins 79-64 +3.9%
4 Milwaukee Brewers 78-66 +2.9%
5 Chicago White Sox 77-66 +1.0%
6 St. Louis Cardinals 77-67 +0.6%
7 Arizona Diamondbacks 76-68 -0.8%
8 Atlanta Braves 75-68 -1.2%
9 Boston Red Sox 75-69 -1.3%
10 Tampa Bay Rays 75-68 -1.5%
11 Pittsburgh Pirates 74-70 -3.7%
12 Colorado Rockies 74-69 -3.9%
13 Baltimore Orioles 73-71 -4.4%
14 Detroit Tigers 71-72 -6.2%
15 Cleveland Guardians 72-72 -6.9%
16 San Diego Padres 70-73 -7.5%
17 Miami Marlins 69-75 -8.7%
18 Philadelphia Phillies 69-74 -8.7%
19 Texas Rangers 70-74 -9.6%
20 Houston Astros 68-76 -9.9%
21 San Francisco Giants 66-78 -14.5%
22 Athletics 66-78 -14.8%
23 Toronto Blue Jays 65-79 -15.0%
24 Cincinnati Reds 65-78 -15.4%
25 Kansas City Royals 65-79 -15.8%
26 New York Yankees 63-80 -16.3%
27 Seattle Mariners 63-81 -18.2%
28 Los Angeles Dodgers 60-83 -21.0%
29 Los Angeles Angels 57-86 -25.2%
30 New York Mets 58-85 -25.8%

Best Team-Total Under Plays

Rank Team Under Record (O-U) ROI
1 Los Angeles Angels 57-86 +13.3%
2 New York Mets 58-85 +12.9%
3 Los Angeles Dodgers 60-83 +9.6%
4 Seattle Mariners 63-81 +7.0%
5 New York Yankees 63-80 +4.1%
6 Toronto Blue Jays 65-79 +3.9%
7 Kansas City Royals 65-79 +3.4%
8 San Francisco Giants 66-78 +2.8%
9 Cincinnati Reds 65-78 +2.5%
10 Athletics 66-78 +1.2%
11 Miami Marlins 69-75 -1.1%
12 Houston Astros 68-76 -2.1%
13 Philadelphia Phillies 69-74 -2.2%
14 Texas Rangers 70-74 -2.6%
15 San Diego Padres 70-73 -5.3%
16 Detroit Tigers 71-72 -5.7%
17 Cleveland Guardians 72-72 -5.8%
18 Baltimore Orioles 73-71 -7.8%
19 Colorado Rockies 74-69 -8.6%
20 Pittsburgh Pirates 74-70 -9.5%
21 Boston Red Sox 75-69 -10.1%
22 Atlanta Braves 75-68 -10.6%
23 Tampa Bay Rays 75-68 -10.8%
24 Arizona Diamondbacks 76-68 -10.8%
25 St. Louis Cardinals 77-67 -12.1%
26 Chicago White Sox 77-66 -12.7%
27 Milwaukee Brewers 78-66 -13.8%
28 Washington Nationals 80-65 -15.6%
29 Minnesota Twins 79-64 -15.8%
30 Chicago Cubs 82-62 -19.6%

First 5 Innings Run Line Picks

First-5 markets settle after five innings, isolating the starting pitchers and removing bullpen and late-inning noise. Washington has been the standout at 90-55, with St. Louis and Tampa Bay close behind.

Rank Team ATS Record Units ROI
1 Washington Nationals 90-55 +28.30u +16.5%
2 St. Louis Cardinals 85-59 +14.85u +8.5%
3 Tampa Bay Rays 81-62 +10.50u +6.2%
4 Atlanta Braves 79-64 +8.70u +5.2%
5 Detroit Tigers 79-63 +8.10u +4.7%
6 Los Angeles Angels 79-64 +5.15u +3.0%
7 Chicago White Sox 77-66 +1.35u +0.8%
8 Milwaukee Brewers 74-69 -1.85u -1.1%
9 Pittsburgh Pirates 76-68 -2.45u -1.4%
10 San Diego Padres 75-68 -4.90u -2.8%
11 Minnesota Twins 74-69 -5.05u -2.9%
12 Cleveland Guardians 71-73 -9.85u -5.9%
13 Cincinnati Reds 73-70 -10.60u -6.1%
14 San Francisco Giants 73-71 -11.35u -6.5%
15 Miami Marlins 73-71 -11.55u -6.6%
16 Kansas City Royals 71-73 -13.00u -7.5%
17 Philadelphia Phillies 69-74 -14.05u -8.4%
18 Baltimore Orioles 69-75 -16.35u -9.6%
19 New York Yankees 68-75 -16.65u -10.0%
20 Colorado Rockies 67-75 -16.45u -10.0%
21 Arizona Diamondbacks 67-76 -20.65u -12.1%
22 Chicago Cubs 67-77 -20.60u -12.2%
23 Boston Red Sox 66-78 -20.75u -12.4%
24 Toronto Blue Jays 67-77 -22.00u -12.9%
25 Athletics 66-78 -22.20u -13.3%
26 Los Angeles Dodgers 66-77 -24.15u -14.1%
27 New York Mets 65-78 -24.05u -14.2%
28 Texas Rangers 63-81 -29.15u -17.1%
29 Seattle Mariners 61-83 -33.00u -19.6%
30 Houston Astros 61-83 -35.55u -20.5%

First 5 Innings Totals Picks (Over / Under)

The first-5 total tracks only the runs scored through five innings. Texas, Minnesota, and the Chicago Cubs lead the Over side, while Toronto and San Diego flip to strong Under numbers.

Best First-5 Over Plays

Rank Team Over Record (O-U) ROI
1 Texas Rangers 80-59 +7.5%
2 Minnesota Twins 79-58 +7.2%
3 Chicago Cubs 80-62 +5.8%
4 Washington Nationals 77-61 +4.3%
5 Houston Astros 75-59 +4.2%
6 Chicago White Sox 74-63 +0.5%
7 Atlanta Braves 73-64 -0.5%
8 Los Angeles Angels 73-65 -0.8%
9 Milwaukee Brewers 73-65 -1.1%
10 Detroit Tigers 69-66 -3.5%
11 New York Mets 72-68 -3.8%
12 Colorado Rockies 69-66 -4.2%
13 Pittsburgh Pirates 71-68 -4.4%
14 Philadelphia Phillies 70-68 -4.5%
15 Boston Red Sox 69-68 -5.5%
16 San Francisco Giants 69-69 -6.2%
17 Athletics 68-70 -6.4%
18 Arizona Diamondbacks 68-69 -6.9%
19 Miami Marlins 69-71 -7.3%
20 Baltimore Orioles 65-68 -8.0%
21 Seattle Mariners 66-69 -8.4%
22 Cincinnati Reds 67-72 -9.4%
23 Los Angeles Dodgers 67-73 -10.1%
24 Kansas City Royals 67-75 -10.7%
25 Tampa Bay Rays 63-72 -11.6%
26 Cleveland Guardians 60-74 -15.2%
27 St. Louis Cardinals 60-76 -17.0%
28 New York Yankees 59-77 -18.1%
29 San Diego Padres 56-82 -24.0%
30 Toronto Blue Jays 56-83 -24.2%

Best First-5 Under Plays

Rank Team Under Record (O-U) ROI
1 Toronto Blue Jays 56-83 +12.0%
2 San Diego Padres 56-82 +11.1%
3 New York Yankees 59-77 +5.5%
4 St. Louis Cardinals 60-76 +4.3%
5 Cleveland Guardians 60-74 +3.6%
6 Tampa Bay Rays 63-72 -0.1%
7 Kansas City Royals 67-75 -0.4%
8 Los Angeles Dodgers 67-73 -1.8%
9 Cincinnati Reds 67-72 -2.7%
10 Baltimore Orioles 65-68 -3.3%
11 Seattle Mariners 66-69 -3.5%
12 Athletics 68-70 -4.6%
13 Arizona Diamondbacks 68-69 -4.6%
14 Miami Marlins 69-71 -5.1%
15 San Francisco Giants 69-69 -5.3%
16 Boston Red Sox 69-68 -6.8%
17 Colorado Rockies 69-66 -7.4%
18 Philadelphia Phillies 70-68 -8.2%
19 Detroit Tigers 69-66 -8.4%
20 Pittsburgh Pirates 71-68 -8.6%
21 New York Mets 72-68 -9.3%
22 Los Angeles Angels 73-65 -10.7%
23 Milwaukee Brewers 73-65 -11.0%
24 Atlanta Braves 73-64 -11.5%
25 Chicago White Sox 74-63 -12.5%
26 Houston Astros 75-59 -15.4%
27 Washington Nationals 77-61 -16.4%
28 Chicago Cubs 80-62 -18.5%
29 Minnesota Twins 79-58 -19.5%
30 Texas Rangers 80-59 -19.9%

Four teams have lost money across the board and belong on the other side of your best bets: the Seattle Mariners (run line minus 18.4 percent, moneyline minus 15.7 percent), the Los Angeles Angels (moneyline minus 16.8 percent), the New York Mets (moneyline minus 15.2 percent), and the Philadelphia Phillies (run line minus 16.4 percent). Note that the Angels are a moneyline fade but lead the league's full-game and team-total Unders, so those angles pair rather than conflict.

Methodology

Every market treats each qualifying game as a flat 1-unit wager settled at the closing line. A win is a cover, a straight-up win, or an Over or Under, depending on the market. Units is the cumulative profit or loss; ROI is units divided by total bets, shown as a percentage. Home and away splits apply the same method to that subset of games. Flat staking keeps all 30 teams on equal footing so a handful of heavy favorites or longshots cannot distort the rankings.

For more MLB picks, parlays, and best bets, visit MLB Picks.

Frequently Asked Questions

Which MLB team has the best run line trend in 2026?

The Tampa Bay Rays lead the league against the run line at 75-65, returning 12.0 percent on flat 1-unit stakes. The Milwaukee Brewers are second at 75-69 (plus 9.7 percent), with Atlanta third, making all three reliable cover teams this season.

Which teams should bettors fade right now?

The Seattle Mariners are the worst run-line team in baseball at 55-88 (minus 18.4 percent), and the Los Angeles Angels have been the biggest moneyline drain at 54-89 (minus 16.8 percent). The Angels are negative on the moneyline and lean Under across the board, so their profile is one to bet against straight up.

What is the difference between the run line and the moneyline?

The moneyline is a straight-up bet on who wins. The run line applies a 1.5-run spread — the favorite must win by two or more, or the underdog must lose by one or win outright. Because so many MLB games are decided by a single run, run-line results often diverge sharply from moneyline records.

Which teams are the strongest Over plays?

The Minnesota Twins top the full-game Over board at 77-57 (plus 8.4 percent), with the Chicago White Sox and Chicago Cubs close behind. The Chicago Cubs and Washington lead the team-total Overs, so those lineups have cleared the number from a different angle.

Which teams are the best Under plays?

The Los Angeles Angels lead full-game Unders at 58-82 (plus 11.8 percent), with Arizona and the New York Yankees close behind. On team totals, the Los Angeles Angels are the strongest Under side at plus 13.3 percent, followed by the New York Mets.

Yes. The first-5 markets isolate the starting pitchers and remove bullpen and late-inning scoring. Washington leads the F5 run line at 90-55, while Toronto and San Diego flip to strong F5 Under sides even though their full-game numbers look different.

These tables reflect the 2026 season through September 8 and are refreshed as new results come in. Records and ROI move daily during the season, so check back before locking in picks.

How is ROI calculated?

Every wager is treated as a flat 1-unit stake at the closing line. Units is the running profit or loss across all of a team's games; ROI is that unit total divided by the number of bets, expressed as a percentage. A positive ROI means backing that side blindly all season would have turned a profit.

Season-long ROI tables are a starting point, not a finished play. A team covering the run line at a strong clip tells you the market has been slow to adjust to how it wins games — but the matchup, the starting pitcher, and the closing number still decide each night. We treat these rankings as a filter: they surface which sides the market has mispriced across a full season, and from there the daily picks come down to the specific game in front of us.

21+. Please play responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER. Odds and records reflect the 2026 MLB season through September 8, 2026 and are subject to change.

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