Chicago State vs Saint Louis Picks and Prediction for Thursday November 6, 2025

By: Cameron Ross Published 11/06/2025, 01:05 AM ET
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Chicago State vs Saint Louis Information

The Chicago State Cougars will again be on the road Thursday night, facing the Saint Louis Billikens in St. Louis, MO. The Chicago State Cougars come into this matchup winless this season, following a 30-point road loss to DePaul in game one. The Saint Louis Billikens stay on their home floor Thursday undefeated after one game, after a 35-point victory to start the year, during the action with our College Basketball Picks.

Chicago State Preview

The Chicago State offense was terrible in game one of the season, scoring just 62 points on 37.5% shooting from the floor. The Cougars lost the rebounding battle by 9, and turned the ball over 16 times in the loss. Marcus Tankersly led the Chicago State offense in game one of the season with 16 points on 11 shots.

Saint Louis Preview

Defensively, Saint Louis was dominant in game one of the year, allowing 67 points on 35.5% shooting. The Billikens won the rebounding battle by 25 and forced 9 turnovers to seal the win. Offensively, St. Louis rolled, scoring 92 points, including 48 in the second half on 49.3% shooting from the floor. Big man Robbie Avila led the offensive show for Saint Louis with 18 points on 13 shots against Southeast Missouri State.

Chicago State vs Saint Louis Prediction

Saint Louis is the far better team in this matchup and will dominate game two of the season on Thursday night. Look for the Billikens to overpower Chicago State on both sides of the ball, leading to another easy win. Take Saint Louis Thursday night to do the job as they get the win and cover in blowout fashion at home. Final Score Prediction, Saint Louis Billikens win and cover 103-61.

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