Duke vs Michigan State Picks and Predictions for Saturday, December 6, 2025

By: David Anicetti Published 12/06/2025, 01:30 AM ET
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The Duke Blue Devils visit the Michigan State Spartans on Saturday. Duke is 9–0 after a 67–66 win over Florida, while Michigan State is 8–0 following a 71–52 victory against Iowa. The Blue Devils are 1–0 away from home, and the Spartans are 5–0 at Breslin Center. Add value to your weekend card with our free college basketball picks.

Duke vs Michigan State Game Information

  • Date: December 6
  • Time: 12:00 PM ET
  • Where: Breslin Center, East Lansing, MI
  • TV: FOX

Duke Blue Devils Outlook

Duke’s frontcourt continues to lead the Blue Devils' offense, with Cameron Boozer carrying the scoring load and also being a strong force on the defensive end. The Blue Devils have been strong in transition and consistent in generating high-percentage looks, while also limiting turnovers by taking care of the ball despite playing uptempo.

Duke is averaging 89.1 points per game while shooting 51.2% from the field and 36.0% from three. The Blue Devils are averaging 42.0 rebounds, 19.4 assists, 5.0 blocks, and 7.4 steals per game. Boozer leads with averages of 23.6 points, 9.3 rebounds, and 3.7 assists, while Patrick Ngongba II adds 12.6 points and 6.3 rebounds along with 1.6 blocks. Isaiah Evans contributes 12.6 points per game as Duke’s second leading scorer.

Michigan State Spartans Outlook

Michigan State has opened the season with steady production in the paint and contributions from multiple players in the backcourt. The Spartans have controlled tempo through disciplined half-court offense and strong defensive rebounding, helping them remain unbeaten.

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Michigan State is averaging 78.6 points per game while shooting 47.4% from the field and 33.3% from three. The Spartans average 41.6 rebounds, 19.4 assists, 4.6 blocks, and 6.8 steals. Jaxon Kohler leads the team with 14.3 points and 9.9 rebounds per game, while Jeremy Fears Jr. adds 12.3 points and a team-high 9.4 assists. Coen Carr contributes 11.3 points and 5.1 rebounds.

Duke Blue Devils vs Michigan State Spartans Prediction

Duke’s frontcourt production and scoring from multiple starters as well as players off the bench, give the Blue Devils a distinct advantage in this matchup of undefeated teams. Michigan State will stay competitive behind Kohler and its interior play, but Duke’s pace, rebounding, and scoring make the difference on the road. Final Score Prediction: Duke Blue Devils win and cover ATS, 82–73. Check out all the sportsbook promos to see if you are getting a great deal on your bets on Michigan State. Make sure you know about how the fans are looking on prediction markets for Duke with the Kickr promo code. Make sure when you place your bet on Michigan State vs Duke you are using the BetMGM bonus code.

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