Friday College Basketball Parlay Picks – December 19 | Two-Leg CBB Parlay

By: Kim Smith Published 12/19/2025, 04:45 AM ET

Friday night’s college basketball slate provides an excellent opportunity to build a parlay around strong home favorites in favorable matchups. With Wisconsin playing on a neutral-leaning home court against a Villanova team coming off a rough road loss, and BYU continuing to dominate lesser competition in Provo, this two-leg college basketball parlay targets teams with clear efficiency and depth advantages.

Check out our parlays, as well as all of our college basketball picks.

College Basketball Parlay

Villanova Wildcats vs Wisconsin Badgers – Wisconsin -5.5
Abilene Christian Wildcats vs BYU Cougars – BYU -33.5

Leg 1 – Villanova Wildcats vs Wisconsin Badgers (Wisconsin -5.5)

Wisconsin enters this matchup looking to bounce back after a lopsided loss at Nebraska, and this sets up as a strong spot for the Badgers to respond. Offensively, Wisconsin has been one of the more efficient scoring teams in the country, averaging over 85 points per game while spreading the floor and getting consistent production from multiple scorers. Playing at Fiserv Forum gives Wisconsin a significant crowd advantage despite Villanova’s strong overall record.

Villanova has played well this season, but their struggles against higher-end competition on the road remain a concern. The Wildcats were overwhelmed at Michigan earlier this month and now face a Wisconsin team that plays at a faster tempo and applies consistent defensive pressure. Wisconsin’s ability to control the pace, generate points in transition, and capitalize at the free-throw line gives them a clear edge. Laying 5.5 points is reasonable in a matchup where Wisconsin should be able to pull away late.

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Leg 2 – Abilene Christian Wildcats vs BYU Cougars (BYU -33.5)

BYU continues to look every bit like a top-10 team, and this matchup against Abilene Christian is a textbook spot for a blowout. The Cougars are averaging nearly 86 points per game while holding opponents to just over 65, creating one of the largest scoring margins in college basketball. At home, BYU has been ruthless, winning games by large margins and showing no hesitation in running up the score.

Abilene Christian simply does not have the offensive firepower or depth to stay competitive in this matchup. The Wildcats struggled badly against Arizona earlier this week and now face a BYU team that plays with superior size, athleticism, and shooting efficiency. BYU’s bench depth also allows them to maintain intensity even after rotating starters, which is key when laying a large number. With BYU riding a seven-game winning streak and dominating inferior opponents, covering the -33.5 spread is well within reach.

Parlays offer strong value when the matchups align correctly, and this two-leg college basketball parlay for Friday, December 19 focuses on teams in ideal spots to control the game flow from start to finish. If both favorites perform to expectation, this parlay has a solid chance to cash.

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