Gonzaga vs Kentucky Picks, Predictions, Odds, and Line Movement for Friday December 5 2025

By: Josh Collacchi Updated 12/04/2025, 03:48 PM ET
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The December 5 matchup between the Gonzaga Bulldogs and Kentucky Wildcats at Bridgestone Arena headlines Friday's college hoops slate, bringing together two storied programs seeking resume-building wins. With Gonzaga entering at 6-1 and Kentucky still searching for consistency after an uneven 5–3 start, bettors will find no shortage of angles in this nationally spotlighted matchup.

Below, we break down the odds, line movement, key handicapping insights, and our best bets for this neutral-site showdown. For more analysis, visit our latest college basketball picks.

TLDR: Quick Picks and Prediction

  • Spread Pick: Gonzaga -2.5
  • Total Pick: Under 155
  • Projected Final Score: Gonzaga 78, Kentucky 72

Odds and Line Movement

Current Odds

Team Spread Total
Gonzaga -2.5 (-115) 155.5 (o-110)
Kentucky +2.5 (-105) 155.5 (u-110)

Line Movement - Spread

Date Time Gonzaga Kentucky Public ($, #)
12/04 02:46pm -2.5/-115 +2.5/-105 --

Line Movement - Total

Date Time Over Under Public ($, #)
12/04 02:46pm 155.5/o-110 155.5/u-110 --

Gonzaga and Kentucky: Key Matchups and Game Preview

This neutral-site showdown features two high-profile programs headed in opposite directions early in the 2025–26 season.

Gonzaga enters 6-1 and continues to lean on interior physicality, balanced scoring, and continuity. Graham Ike has again been a pivotal force in the paint, and the Zags’ structure under Mark Few remains one of the most disciplined in the nation. Last year’s overtime thriller in Seattle — a 90–89 Kentucky win — featured Ike dominating inside with 28 points and 11 rebounds. That matchup underscored Gonzaga’s advantage in the paint, an area that looms large again here.

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Kentucky sits at 5-3 and is reeling after being thoroughly outplayed on the glass by North Carolina. The Wildcats’ rim protection and rebounding remain glaring concerns, and head coach Mark Pope continues to shuffle rotations due to inconsistent perimeter shooting and fluctuating defensive intensity. While no new major injuries have been reported, Kentucky’s issues have been structural rather than personnel-based.

Gonzaga’s stability is the clear contrast. Their ball movement, interior scoring, and rebounding edge match up favorably against a Kentucky squad struggling to establish its identity. In a matchup where tempo may fluctuate, the Zags’ ability to control the half-court game offers a measurable advantage.

  • GON: 6-1 in non-conference play
  • GON: Strong interior scoring and rebounding metrics continue to define their early-season profile.
  • UK: 5-3 this season with significant defensive struggles against quality opponents.
  • Series: Kentucky won last year's meeting 90-89 in OT; series tied all-time.

Key Injuries and Things To Know (GON vs UK)

  • Gonzaga: No new injuries reported.
  • Kentucky: No fresh injuries, but roster depth and interior presence remain concerns.

Side and Over/Under Picks

  • Spread Pick: Gonzaga -2.5
  • Total Pick: Under 155

Final Score Prediction

Gonzaga 78, Kentucky 72

How to Wager on Gonzaga vs Kentucky

For bettors targeting this marquee matchup, several angles stand out. Gonzaga’s interior scoring and rebounding edge suggest value on the Zags at a short number, while Kentucky’s offensive inconsistency and struggles defending the paint lean strongly toward an under play if the pace tightens.

Before placing your wager, explore the latest offers:

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