Kentucky vs. Louisville Picks and Prediction for Tuesday, November 11, 2025

By: Dylan Hellebrand Published 11/11/2025, 02:10 AM ET
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On Tuesday, the Kentucky Wildcats (2-0) face off against the Louisville Cardinals (2-0) at KFC Yum! Center in Louisville, Kentucky. This game will air on ESPN. Keep up to date with all the NCAAB action, with our College Basketball predictions.

Kentucky vs Louisville Game Information

  • November 11, 2025
  • 8:00pm EST
  • KFC Yum! Center
  • ESPN

Louisville Form & Recent Results

Louisville has started their season on a high note, picking up victories in both of their opening games. In their impressive 106-70 win over Jackson State, Ryan Conwell stood out by putting up 19 points for the Cardinals. Early on, Khani Rooths has emerged as the team’s top scorer, averaging 18 points per game, while Ryan Conwell isn’t far behind, averaging 15.5 points. On the glass, J’Vonne Hadley has been making his presence known, leading the team with an average of 9 rebounds per game. When it comes to setting up his teammates, Mikel Brown Jr. has been the Cardinals’ main playmaker, dishing out an average of 7.5 assists. With Louisville posting an impressive average of 105 points through their first two games, they now gear up for one of their toughest challenges of the season as they go head-to-head with a talented Kentucky Wildcats squad. Louisville and Kentucky always put up a great game and that is what you can get into by checking out the social sportsbooks.

Kentucky Form & Recent Results

Kentucky has started the season strong, picking up two wins in their first two games. In their impressive 107-59 victory over Valparaiso, Malachi Moreno led the scoring for the Wildcats with 18 points. So far this season, Collin Chandler has been Kentucky's top scorer, averaging 14.5 points per game, while Otega Oweh isn’t far behind, putting up an average of 14 points. On the boards, Moreno has been a standout, collecting an average of 9.5 rebounds to lead the team. Jaland Lowe has been the main playmaker, dishing out an average of 5 assists per game. Over their first two games, the Wildcats have put up an average of 92 points and will look to keep that offensive firepower going as they travel to face Louisville, aiming for another big win away from home. Be sure you are using the best sportsbooks to find all the betting action that Kentucky has available.

Key Players

  • Kentucky’s Malachi Moreno: 18 points in last game, 9.5 rebounds per/g
  • Louisville’s Ryan Conwell: 19 points in last game, 15.5 points per/g

Betting Odds & Market Overview:

  • LOU -3.5, O/U 174.5

Kentucky vs Louisville Picks and Prediction

Louisville and Kentucky are both aiming to keep their perfect records intact as they meet in what promises to be a thrilling rivalry game. Louisville is counting on the support from their home crowd to help push them to victory, hoping the familiar court gives them an edge. On the other side, Kentucky is determined to prove themselves in their first away matchup of the season, looking to leave Louisville with a hard-fought win and stay unbeaten. Final Score Prediction, Louisville Cardinals win and cover the spread, 82-73. Kentucky vs Louisville is always a great rivalry game and one that you can bet on using the Fanatics Sportsbook promo code.

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