Louisville vs. Cincinnati Picks and Predictions for Friday November 21, 2025
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On Friday, the Louisville Cardinals (4-0) face off against the Cincinnati Bearcats (4-0) at Heritage Bank Center in Cincinnati, Ohio. This game will air on ESPNU. Keep up to date with all the NCAAB action, with our College Basketball predictions.
Louisville vs. Cincinnati Game Information
- November 21, 2025
- 6:30pm EST
- Heritage Bank Center
- ESPNU
Cincinnati Form & Recent Results
Cincinnati heads into this matchup riding a strong start, having come out victorious in their first four games of the season. In their most recent game, the Bearcats put together a 72-55 win over Mount St. Mary’s, with Day Day Thomas leading the charge and putting up 16 points. So far this season, Baba Miller has emerged as Cincinnati’s top scorer, averaging 15.8 points per game, while Day Day Thomas isn’t far behind with an average of 14 points. Miller has also been a force on the boards, grabbing an average of 10.5 rebounds each game to lead the team in that category. When it comes to setting up his teammates, Kerr Kriisa has been the Bearcats’ go-to playmaker, averaging 5 assists per game. Through these first four contests, Cincinnati has averaged an impressive 78.5 points per game. Now, they’re looking to keep that momentum going as they welcome one of the country’s top teams, Louisville, to their home court. Check out all the sportsbook promos to see if you are getting a great deal on your bets on Cincinnati.
Louisville Form & Recent Results
Louisville comes into this game riding a wave of momentum, having started their season with four straight wins, just like Cincinnati. In their most recent victory, a 106-81 triumph over Ohio, Ryan Conwell delivered an impressive performance, putting up 22 points for the Cardinals. Throughout this young season, both Conwell and Mikel Brown Jr. have been the driving force behind Louisville’s offense, each putting up an average of 19.3 points per game. Isaac McKneely isn’t far behind, contributing 12.3 points per contest. When it comes to hitting the boards, J’Vonne Hadley has been Louisville’s standout, averaging 7 rebounds each game, providing a strong presence in the paint. Mikel Brown Jr. has also been a key playmaker, dishing out an average of 6.8 assists to help keep the offense running smoothly. Louisville has been lighting up the scoreboard so far, pouring in an average of 103 points over their first four games. They’ll be aiming to keep that hot streak going and maintain their unbeaten record as they head out to face Cincinnati, who are also yet to lose a game this season. Make sure you know about how the fans are looking on prediction markets for Louisville with the Kickr promo code.
Key Players
- Louisville’s Mikel Brown Jr. this season: 19.3 points, 6.8 assists per game
- Cincinnati’s Baba Miller this season: 15.8 points, 10.5 rebounds per game
Betting Odds & Market Overview:
- LOU -8.5; O/U 163.5
Cincinnati vs Louisville Picks and Prediction
Both Louisville and Cincinnati have yet to lose a game this season, making this weekend’s matchup all the more exciting. While Louisville is currently recognized as one of the nation's powerhouse teams, Cincinnati sees this home game as the perfect opportunity to pull off a major upset. Final Score Prediction, Louisville Cardinals win, but fail to cover the spread, 71-70. Make sure when you place your bet on Cincinnati vs Louisville you are using the BetMGM bonus code.
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