Louisville vs Clemson Picks and Predictions for Saturday, February 28, 2026
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Louisville vs Clemson Information
The Louisville Cardinals will be on the road again Saturday afternoon with the 2:00 PM match-up inside Little John Coliseum in Clemson, SC, against the Clemson Tigers. Louisville is the #24-ranked team in the nation with 20 wins and 8 losses this season, having lost 2 of the last 3 after a 3-point road loss to North Carolina. The Clemson Tigers stay home Saturday with twenty wins and losses this season, riding a four-game skid following the five-point home loss to Florida State in their last outing. Stay in the action with our College Basketball Picks.
Louisville Preview
Offensively, Louisville is averaging 86.4 points on 47% shooting from the floor this season. Defensively, the Cardinals have been solid enough, holding opponents to 72 points per game this year, but have given up an average of 86 points per game over their last two losses. Ryan Conwell leads the Louisville offense this season, averaging 18.5 points per game. Mikel Brown Jr. has averaged 18.9 points per game this season for Louisville, but has played just 20 times. J’Vonne Hadley averages 11.3 points, and Isaac McNeely is 4th on the team with 10.6 points per game. Sananda Fru averages 9.6 points to go along with the team-leading 6.4 rebounds per game.
Clemson Preview
Offensively, Clemson is averaging 74.5 points on 46% shooting from the floor this season. Defensively, the Tigers have been solid, holding opponents to 65.6 points per game this year, but had given up an average of 74.5 points per game during their current 4-game losing streak. RJ Godfrey leads the Clemson offense this season, averaging 11.5 points per game. Carter Welling is second on the roster with 10.3 points to go along with the team-leading 5.6 rebounds. Jestin Porter averages 9.7 points, and Nick Davidson is 4th on the team with 9.2 points per game. Dillon Hunter averages 7.7 points to go along with the team-leading 3 assists per contest.
Louisville vs Clemson Prediction
Both teams come into this matchup with the same record, but Louisville is the far better team. The Cardinals have an elite offense that will end their recent skid. Look for Louisville to run it up Saturday afternoon if they do the job against a struggling Clemson team. Take the Louisville Cardinals on Saturday afternoon to get the win and cover on the road against the Clemson Tigers.
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Best Picks:
- Louisville Cardinals ATS
- Over
