Michigan State vs Duke Picks and Prediction for Tuesday November 10 2026

By: Kim Smith Published 11/10/2026, 12:00 AM ET

Michigan State and Duke meet Tuesday night at the United Center in Chicago for the Champions Classic. ESPN has the 7 PM ET tip. Duke is laying 6.5 points, and the total is 148.5. Both teams are undefeated, both have been scoring like crazy, and neither has faced anything close to this kind of competition yet. That’s what makes the number interesting. I think Duke probably wins. Six and a half points against Michigan State on a neutral floor? That’s asking a little more. Get ready for all the action with our free college basketball picks.

Michigan State Has More Than Enough to Make This Interesting

Michigan State is 2-0, ranked sixth nationally, and coming off two comfortable victories. The Spartans have scored 187 points through their first two games. That’s 93.5 a night. It’s early, obviously, and nobody should confuse those opening opponents with Duke. But Michigan State has been playing the kind of basketball Tom Izzo likes. Rebound, share the ball, and make the other team work.

The Spartans are shooting 54.6% from the floor and 40.4% from three. They’ve also been grabbing 44.5 rebounds a game, including 14 on the offensive glass. That’s the part Duke needs to worry about. Michigan State can get a second or third chance on a possession, and those extra opportunities add up. Defensively, the Spartans have allowed only 60 points per game, although that number is going to get a serious test Tuesday.

Jeremy Fears Jr. is the guy I want to watch. He’s the guard who can settle Michigan State down when things get hectic, and that’s going to matter against Duke’s pressure. The Spartans don’t want to get into a game where they’re taking hurried shots and turning the ball over. If Fears can get them into their offense and Michigan State holds its own on the glass, I think the Spartans can hang around all night.

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Duke Has Looked Pretty Good, Too

Duke is 2-0 and ranked second in the country. The Blue Devils have been beating up on their early opponents, averaging 98.5 points a game. That’s a lot of offense, and they’ve been doing it with a young roster that still has plenty of room to improve. The talent is obvious. The question is what happens when somebody finally pushes back.

Duke is shooting 55.4% from the floor, and the Blue Devils have been getting to the foul line more than 33 times per game. They’ve also been forcing turnovers and creating easy baskets. That’s a dangerous combination. Michigan State has been excellent on the boards, though, and Duke isn’t going to get every rebound or every open look it has enjoyed so far.

Patrick Ngongba II is averaging 19 points and eight rebounds, while Cayden Boozer has been handing out 7.5 assists a game. Those two give Duke a nice combination of inside scoring and ball movement. Ngongba could be a real problem if Michigan State gets into foul trouble. But Duke’s younger players are also getting their first big neutral-court test. I wouldn’t be shocked if the Blue Devils have a few rough stretches.

Michigan State vs Duke Picks and Prediction

Spread Pick: Michigan State +6.5

Give me Michigan State and the 6.5 points. Duke has more than enough talent to win, and I wouldn’t argue with somebody taking the Blue Devils straight up. But Michigan State has been rebounding like crazy, and Izzo usually has his teams ready for these early-season games. The Spartans are averaging 14 offensive rebounds. That’s a lot of extra possessions to hand a team that’s getting nearly seven points. Duke could pull away if its pressure forces turnovers, and that’s the danger. I just think this one stays closer than the number suggests.

Total Pick: Under 148.5

I’m going under 148.5. I know both teams have been scoring in the 90s, but look at who they’ve played. Neither defense is going to give up the same easy looks Tuesday. Michigan State wants to rebound and make Duke work, while Duke has the length to disrupt the Spartans’ offense. There will be some transition baskets, sure. But I think this looks more like a 76-70 game than a 90-85 shootout.

Final Picks: Michigan State +6.5 | Under 148.5

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