Missouri vs Notre Dame Picks and Predictions for Tuesday December 2, 2025

By: Kim Smith Published 12/02/2025, 03:00 AM ET

Missouri travels to South Bend to face Notre Dame at Purcell Pavilion, with tipoff set for 9:00 PM EST on ESPNU. Missouri enters undefeated at 8-0, while the Irish look to stay perfect at home and attempt to hand the Tigers their first loss. Make sure you check out the full and free college basketball picks.

Missouri Preview

The Tigers sit at 8-0 and have dominated nearly every matchup so far. Their latest win was an 86-59 victory over Cleveland State, continuing a stretch in which the offense and defense have both been extremely efficient.

Missouri is averaging 92.9 points per game while shooting 56% from the field. Defensively, they’re allowing just 68.1 points per contest, with 3.3 blocks and 8.8 steals per outing. The Tigers clean up on the glass with 41.5 rebounds, and the offense flows with 16.8 assists per game. Betting on sports and on Missouri is easy, but even easier if you use the best sportsbooks.

Notre Dame Preview

Notre Dame enters at 5-3 and is undefeated at home with a 4-0 mark at Purcell Pavilion. Their most recent game was a 66-56 loss to Houston, but the Irish have shown strong competitiveness early in the season despite a challenging schedule.

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The Irish are averaging 75.4 points per game on 46% shooting, while allowing 67.3 points per contest. Defensively, they have posted 1.6 blocks and 5.4 steals per outing. Notre Dame grabs 37.6 rebounds, and their offense produces 11.5 assists per game. Make sure you know how the fans are looking on prediction markets for Notre Dame with the Novig promo code.

Missouri vs Notre Dame Pick

I’m taking Missouri in this matchup. Notre Dame is strong at home, but Missouri has been playing on a different level so far — their scoring efficiency, rebounding advantage, and overall defensive energy absolutely jump off the page. The Tigers’ depth and pace are going to challenge a Notre Dame team that can go stagnant offensively for stretches.

Notre Dame may keep this competitive early, especially with their home-court shooting boost, but Missouri’s firepower and defensive pressure should tilt the game late. Give me Missouri to stay undefeated and get the win. The best sportsbooks are the best way to go when you are betting on Missouri. Make sure you know about how the fans are looking on prediction markets for Notre Dame with the Onyx Odds promo code. Getting the most out of your bets on Missouri vs Notre Dame can be done by using the Fanatics Sportsbook promo code.

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