Ohio vs Louisville Picks and Predictions for Saturday, November 15, 2025

By: David Anicetti Published 11/15/2025, 12:35 AM ET
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Ohio visits No. 12 Louisville on Saturday at the KFC Yum! Center. The Bobcats are 1–2 after losses to Saint Mary’s and Arkansas State, with a home win over Illinois State, while Louisville is 3–0 with all three wins coming at home, including a rivalry victory over Kentucky. Build your bankroll with our college basketball picks.

Ohio vs Louisville Game Information

Date & Time: Saturday, November 15, 12:00 PM ET

Where: KFC Yum! Center, Louisville, KY

TV: The CW Network

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Team Breakdown - Ohio Bobcats 

Ohio is averaging 72.3 points per game while allowing 82.3, and the defensive struggles have been the difference in the two losses. The Bobcats are shooting 45.6% from the field but have had trouble on defense, especially on the road. Ohio has averaged just 29.7 rebounds per game, and the lack of second-chance opportunities has limited its ability to keep pace in higher-scoring matchups.

The Bobcats have also averaged only 12.0 assists per game, and long scoring droughts have shown up in each of their losses. Ohio has dropped two of its last three and has yet to play well away from home. Ohio does not have any players on its injury report. Make sure you know about how the fans are looking on prediction markets for Ohio with the Thrillz promo code.

Ohio — Key Stats & Leaders

  • Scoring Leader: Jackson Paveletzke – 18.0 ppg
  • Rebounding Leader: Aidan Hadaway – 5.7 rpg
  • Assists Leader: Jackson Paveletzke – 4.0 apg
  • Team Shooting: 45.6% FG, 25.9% 3-point

Team Breakdown - Louisville Cardinals

Louisville is averaging 102.0 points per game and allowing 67.7, opening the season with three straight wins by controlling the pace and attacking from multiple spots on the floor. The Cardinals are shooting 50.0% overall and have shown excellent ball movement with an average of 22.3 assists per game. Louisville has also rebounded well at 45.3 per contest and has been tough on defense, averaging 11.3 steals.

The Cardinals have won five straight, dating back to last season at home, and have dominated the first half in each game. Louisville’s deep bench and shooting have made them tough to slow down, especially at home. Louisville does not have any injuries. Make the most of your bets on Louisville by using the sportsbook promos.

Louisville — Key Stats & Leaders

  • Scoring Leader: Mikel Brown Jr. – 19.3 ppg
  • Rebounding Leader: Sananda Fru – 6.7 rpg
  • Assists Leader: Mikel Brown Jr. – 6.7 apg
  • Team Shooting: 50.0% FG, 33.3% 3-point

Ohio vs Louisville Prediction

Louisville has the stronger offense, deeper bench, and better numbers in every major team category. Ohio has struggled to defend and rebound on the road, and keeping up with Louisville’s pace will be difficult for four full quarters. Final Score Prediction: Louisville Cardinals win and cover ATS, 98–70. Make sure when you place your Ohio vs Louisville bet you are using the bet365 bonus code.

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