Purdue vs Northwestern Picks and Predictions for Wednesday March 4 2026

By: Jeremy O'Quinn Published 03/04/2026, 02:25 AM ET
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Purdue Preview

The Purdue Boilermakers are heading to Welsh-Ryan Arena on Wednesday, where they will take on the Northwestern Wildcats. Get the rest of our free college basketball picks here! The Purdue Boilermakers enter this Big Ten Conference matchup with a 22-7 overall record and a 12-6 mark in Big Ten play, positioning them as one of the stronger teams in the league. Purdue has been a high-powered offense this season, averaging 82.3 points per game while shooting nearly 50% from the field, and they’ve distributed scoring effectively (ranking near the top nationally in assists at 19.6 per game) led by Braden Smith with 8.7 assists per game. Defensively, the Boilermakers allow about 72.5 points per game, giving them a strong scoring margin with balance across their rotation.

Northwestern Preview

The Northwestern Wildcats currently sit with a 13-16 overall record and a 5-13 mark in Big Ten play, but they’ve been competitive recently, riding a three-game winning streak, including a 63-62 road upset of Oregon in their most recent outing. Northwestern averages 73.7 points per game, and its leading scorer Nick Martinelli is averaging roughly 22.5 points and 6.3 rebounds per game, ranking among the top individual performers in the conference. Defensively, the Wildcats allow around 69.9 points per contest, giving them a chance to stay in games if they can limit turnovers and control pace.

Northwestern vs Purdue Prediction

Northwestern heads into Wednesday on the hunt for their fourth consecutive victory, while the 15th ranked Boilermakers hope to avoid a third straight loss. Expect Northwestern to compete in this game and cover the +10.5 spread, however Purdue takes the win. Final score prediction, Purdue wins 79-75.

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