San Diego State Aztecs vs Grand Canyon Lopes Picks and Prediction for Wednesday January 21 2026
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The San Diego State Aztecs travel to Phoenix to take on the Grand Canyon Lopes at Global Credit Union Arena on Wednesday, January 21, 2026, with tipoff scheduled for 11:00 PM EST. This late-night nonconference matchup will be televised nationally on FS1. At the time of this writing, moneyline odds were not released for this game. The total is set at 143.5 points with both the Over and Under priced at -110, while San Diego State enters as a slim 1.5-point road favorite. Be sure to check out our free college basketball picks for more daily college hoops betting insight.
Aztecs Bring Momentum into the Desert
San Diego State comes into this matchup riding strong form, having won five straight games. Over their last five contests, the Aztecs have recently won over New Mexico, Fresno State, and Boise State in a triple-overtime thriller, while also picking up road victories against the Cowboys and Nevada, showing both resilience and depth.
From a statistical standpoint, San Diego State is averaging 82.0 points per game while allowing 72.2 points per contest. The Aztecs are shooting an efficient 48% from the field and averaging 37.4 rebounds per game, giving them balance on both ends of the floor.
Defensive pressure remains a key strength for San Diego State. The Aztecs average 8.1 steals and 4.6 blocks per game, using their athleticism to disrupt passing lanes and protect the rim, which often fuels transition scoring opportunities.
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Lopes Look to Defend Home Court
Grand Canyon enters Wednesday night with an 11-6 overall record and has been competitive at home this season. In their last five games, the Lopes have recently beaten Utah State, San Jose State, and Boise State, while also losing to New Mexico on the road and dropping a home game against Colorado State.
Offensively, Grand Canyon is averaging 75.4 points per game while allowing 68.9 points per contest. The Lopes are shooting 44% from the field and pulling down 36.2 rebounds per game, relying on physical play and half-court execution.
Defense has been a steady component of Grand Canyon’s success. The Lopes limit opponents’ efficiency and average 6.9 steals per game, helping them stay competitive even against higher-powered offenses.
Aztecs vs Lopes Pick
San Diego State Aztecs vs Grand Canyon Lopes Pick
- Pick: San Diego State -1.5
San Diego State’s current form, offensive efficiency, and defensive pressure give them a slight edge in what should be a competitive matchup. The Aztecs have proven they can win close games, both at home and on the road, and their ability to force turnovers could be the deciding factor late. Laying the small number with San Diego State is the preferred play.
San Diego State Aztecs vs Grand Canyon Lopes Total Pick
- Pick: Over 143.5
I am taking the Over in this matchup because both teams are capable of scoring efficiently, and San Diego State has been playing at a faster pace during its winning streak. With Grand Canyon also able to contribute offensively at home, this game has a strong chance to push past the 143.5 total.
Final Score Prediction:
San Diego State 75, Grand Canyon 71
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