San Francisco at Saint Louis — Picks & Prediction for Saturday, December 13, 2025

By: Garrett Beaverson Published 12/13/2025, 05:30 AM ET
Use Code PPWC

The San Francisco Dons travel to St. Louis to take on the Saint Louis Billikens on Saturday, December 13, 2025. Get in on the action with our free college basketball picks.

San Francisco Dons Analysis

San Francisco comes into this matchup having just earned a road win over Mississippi State, grabbing a 65-62 victory in their last outing thanks to strong rebounding and solid defense.

Key Team Metrics & Style

  • Record: 6-4 overall, 0-1 away.

  • Scoring & Efficiency: USF averages ~75 points per game, with Ryan Beasley leading at about 13.0 PPG, while Mookie Cook contributes about 11.7 PPG.

    Sign Up Get $30 Premium Picks Credit + Exclusive Offers

    Subscribe Now

    I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.
  • Rebounding: They secure around 38 rebounds per game, but defensive rebounding is a pressure point — 25.4 defensive boards per game, below what Saint Louis gets.

Strengths

  • Balanced scoring: Four players average close to double figures, giving them offensive options and spacing.

  • Recent momentum: A tight road win over Mississippi State shows the Dons can close on the road when locked in.

  • 3-point prowess: San Francisco leads the WCC in made triples per game, making them dangerous from range.

Weaknesses / Risks

  • Rebounding deficit vs. elite boards: With Saint Louis averaging over 40 rebounds per game, U.S.F. could be overwhelmed on the glass.

  • Road struggles and hostile environment: A 0-1 road mark and the challenge of Chaifetz Arena’s crowd could sap confidence early.

  • Defense vs high-tempo offense: Saint Louis pushes pace, a tough test for San Francisco’s transition and perimeter containment.

Saint Louis Billikens Analysis

Saint Louis looks like one of the country’s most prolific offenses early, combining scoring balance with rebounding dominance and efficient defense.

Team Strengths & Style

  • Record: 8-1 overall, 6-0 at home.

  • Scoring: They lead the nation in scoring, averaging about 91.6 points per game on offense.

  • Rebounding & Defense: Saint Louis is top-tier in rebounding margin (+12.9) and allows only about 37.2% shooting on defense.

  • Balanced Attack: Robbie Avila and Dion Brown each average ~12.4 PPG, with Trey Green, Amari McCottry, and Quentin Jones also chipping in.

Strengths

  • Home dominance: A perfect home record and comfortable role as A-10 leader gives them confidence and crowd support.

  • Offensive variety: They can score inside and out, big and small, thanks to rotation depth and balanced scoring.

  • Rebounding control: Their rebounding edge should limit second-chance opportunities for San Francisco.

Weaknesses / Risks

  • Turnovers can hurt: High-tempo offenses sometimes trade possessions; careless ball security could allow San Francisco easy shots.

  • Pressure to sustain scoring: Against disciplined defenses, they must maintain efficiency and shot selection.

Standout Players & Key Matchups

  • San Francisco:

    • Ryan Beasley — lead scorer and facilitator, can create his own shot and push tempo.

    • Mookie Cook — secondary scorer and versatile rebounder, gives USF physicality.

  • Saint Louis:

    • Robbie Avila — scoring and playmaking leader, key to tempo and offensive rhythm.

    • Dion Brown — top rebounder and efficient scorer, anchors their inside game.

Saint Louis vs San Francisco Prediction Reasoning

This game features a contrast in styles — San Francisco’s balanced scoring and perimeter shooting against Saint Louis’s elite offense, rebounding, and home strength. Saint Louis’s ability to control tempo, rebound, and score in bunches makes them a tough matchup, especially in front of a supportive home crowd. San Francisco’s balanced attack and recent road win gives them tools to compete, but the Billikens’ depth and efficiency should prevail late. The best sportsbooks are the best way to go when you are betting on Saint Louis. Make sure you know about how the fans are looking on prediction markets for San Francisco with the Onyx Odds promo code. Getting the most out of your bets on Saint Louis vs San Francisco can be done by using the Fanatics Sportsbook promo code.

Final Score Projection: Saint Louis 92, San Francisco 80

Betting on College Basketball?

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
Video: Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026

Best Picks

  • Saint Louis -10.5
  • Over 152.5 total points
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.