San Francisco vs Minnesota Picks and Predictions for Saturday, November 22, 2025

By: David Anicetti Published 11/22/2025, 12:30 AM ET
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San Francisco heads to Sioux Falls on Saturday to face Minnesota as both teams look to build on strong starts. The Dons are 4–1 and riding a three-game winning streak after beating Northwestern State 84–64. Minnesota is also 4–1 and coming off wins over Charleston Southern and Green Bay, led by one of the nation’s top scorers in Cade Tyson. Cash in when playing our college basketball picks.

San Francisco vs Minnesota Game Information

  • Date & Time: Saturday, November 22, 5:30 PM ET
  • here: Sanford Pentagon, Sioux Falls, SD
  • TV: Peacock

San Francisco Dons Preview

San Francisco is averaging 81.4 points per game while shooting 48% from the field. Ryan Beasley leads the Dons with averages of 14.0 points, 2.8 assists, and 2.0 steals, giving them a guard who pushes pace and can finish at the rim. Mookie Cook adds 13.2 points and 6.2 rebounds and has been strong from mid-range and around the basket. David Fuchs adds 10.2 points and 6.6 rebounds, giving San Francisco interior scoring and second-chance looks.

Defensively, the Dons allow only 65.4 points per game while generating 8.4 steals and 4.2 blocks. The defense is strong at several positions, and ball pressure has helped them build early leads in recent wins. San Francisco has also shot the ball well from deep, with multiple guards above 40% from three, helping them stretch defenses and open driving lanes. The best sportsbooks are the best way to go when you are betting on San Francisco.

Minnesota Golden Gophers Preview

Minnesota is averaging 76.0 points per game while giving up just 62.4, leaning heavily on Cade Tyson, who leads the team with an average of 23.4 points on 53.3% shooting. Jaylen Crocker-Johnson adds 12.0 points and 12.0 rebounds, giving the Gophers a consistent presence inside. Isaac Asuma averages 10.6 points and 4.8 assists per game and has been reliable as a primary playmaker in the halfcourt.

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The Gophers generate 8.2 steals and 3.2 blocks, allowing them to stay in control defensively even when the offense slows. Chansey Willis Jr. adds 2.8 steals, providing quick hands at the top of the defense. Minnesota has won four of its last five with guard scoring, strong defensive numbers, and improvement on the boards from its frontcourt players. Make sure you know about how the fans are looking on prediction markets for Minnesota with the Onyx Odds promo code.

San Francisco vs Minnesota Prediction

San Francisco has shot the ball well and shown good overall balance, but Minnesota’s combination of Tyson’s scoring, a strong rebounding advantage, and reliable backcourt play gives the Gophers an upper hand in a neutral-site game. Both teams defend well, but Minnesota’s inside presence should make the difference late. Final Score Prediction: Minnesota Golden Gophers win and cover ATS, 74–68. Getting the most out of your bets on San Francisco vs Minnesota can be done by using the Fanatics Sportsbook promo code.

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