South Carolina State vs Louisville Picks and Predictions for Monday, November 3, 2025

By: Cameron Ross Published 11/03/2025, 02:40 AM ET
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South Carolina State vs Louisville Information

The South Carolina State Bulldogs will be on the road Tuesday night for game one of the regular season inside the KFC Yum! Center and 9:00 PM against the Louisville Cardinals. South Carolina State comes into this season looking to build off a strong campaign a year ago, as they finished with twenty wins and 13 losses overall after a one-point loss to Norfolk State in the final game of the year. The Louisville Cardinals had a strong campaign a year ago, finishing the season with 27 wins and eight losses after a 14-point loss to Creighton in the first round of the NCAA tournament. Stay in the news with our College Basketball Picks.

South Carolina State Preview

Colin McKenzie is the top scorer returning from a year ago after averaging 5.8 points in just over 14 minutes per game. South Carolina State was tremendous on offense a year ago, ranking 47th in the country and averaging 79.5 points on 46.8% shooting from the floor. Defensively, South Carolina state had some issues, ranking 1:30 in the country, allowing 70.4 points on just over 44% shooting from the floor.

Louisville Preview

Louisville will welcome the 25th-best recruiting class in the nation for the 2025-2026 season. J’Vonne Hadley is the top returning scorer back from last season after averaging 12.2 points and a team high 7.3 rebounds per game. The Louisville defense anchored the team last season, ranking 90th in the country, holding opponents to 69.4 points per game on less than 43% shooting. Offensively, Louisville was stout after 28.4 points on 45.3% shooting, ranking 65th in the country.

South Carolina State vs Louisville Prediction

Louisville comes into this season as one of the best teams in the country and will open the season Tuesday night with a bang. Look for the Cardinals to dominate this game on both sides of the ball as they roll past South Carolina State. Take Louisville to do the work and blow out fashion as they get the easy home win and cover to start the new year. Final Score Prediction, Louisville Cardinals win and cover 103-56.

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Best Picks:

  • Louisville Cardinals -33.5
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