Southern Indiana Screaming Eagles vs Eastern Illinois Panthers Picks & Prediction for Saturday, February 21, 2026

By: Thomas Pemberton Published 02/21/2026, 03:00 AM ET

The Southern Indiana Screaming Eagles head to Eastern Illinois on Saturday to take on the Panthers. Tipoff is scheduled for 4:30 PM est at the Lantz Arena. Eastern Illinois beat Southern Indiana 59-51 back in January in their last meeting. Eastern Illinois is coming off of a loss. While Southern Indiana won their last game. Stay up to date with our expert's Free College Basketball Picks Here.

Screaming Eagles Hope To Build Off Win

The Southern Indiana Screaming Eagles beat Western Illinois 77-70 in their last game played to snap a six game losing streak. Amaree Brown led the way in the win with 18 points. Brown is averaging 13.9 points per game. The Screaming Eagles have five players averaging double digit points scored per game. Southern Indiana 6-21 on the season with a 3-9 road record. The Screaming Eagles have won just two of their last ten games. Southern Indiana is scoring 68.8 points scored per game with 7.7 made three pointers.

Panthers Hoping To Bounce Back After A Loss

The Eastern Illinois Panthers are 11-17 on the season. The Panthers are 9-5 on their home court and are 4-6 over their last ten games. Eastern Illinois is averaging 67.3 points scored per game with 5.6 made three pointers. The Panthers are averaging 7.7 steals per game. Eastern Illinois lost to Morehead State 73-70 in their last game played. Zion Fruster led the way in the loss with 18 points and 5 assists. Fruster leads the Panthers on the season with 14.7 points scored per game. Eastern Illinois has four players averaging double digit points scored per game.

Southern Indiana vs Eastern Illinois Spread Pick

Eastern Illinois Panthers -4

The Eastern Illinois Panthers are a -4 home favorite on Saturday. The Panthers are looking to beat the Screaming Eagles in back to back months. Southern Indiana has been awful on the season but half of their wins do come on the road. The Panthers play their best basketball on their home court.

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Southern Indiana vs Eastern Illinois Over/Under Pick

UNDER 133.5

The over/under is set at 133.5 points in this Saturday matchup. Both Southern Indiana and Eastern Illinois have had their struggles this season. Both teams have not found consistent success on the offensive side of the court. Watch for a tight game but a low scoring game.

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