UConn vs Michigan Picks and Prediction for Friday November 6, 2026

By: Cameron Ross Published 11/06/2026, 12:50 AM ET

The UConn Huskies will be on the road Friday night for a neutral-site matchup against the No. 16 Michigan Wolverines inside TD Garden in Boston, Massachusetts. The game is scheduled to tip off at 8:00 PM ET. UConn enters its second game of the season undefeated after a dominant 40-point home win in its season opener. Michigan is also undefeated after opening the year with a nearly 20-point victory against Oakland. UConn enters Friday night as a 5.5-point favorite at -230 on the moneyline, while Michigan is listed at +190. The total is set at 145.5 points. Stay in the action with our College Basketball Picks.

UConn Preview

The UConn Huskies rolled in their season opener, pouring in 86 points, including 43 in each half, on 52% shooting from the floor. Defensively, the Huskies were just as dominant, allowing only 46 points on 26% shooting. UConn controlled the glass, winning the rebounding battle by double digits, and forced 17 turnovers in the blowout victory.

Braylon Mullins led the UConn offense with 20 points on 12 shots. Nik Khamenia chipped in 14 points on 11 shots, while Na’Jai Hines was the third starter in double figures with 12 points on six shots in 22 minutes. Colben Landrew led the way off the UConn bench with 11 points on six shots in 22 minutes of action. The rest of the Huskies' bench combined for 17 points on 15 shots, giving UConn balanced offensive production throughout the lineup.

Michigan Preview

The Michigan offense did the work in its season opener, pouring in 84 points on 44% shooting from the floor. Defensively, Michigan was phenomenal, allowing just 68 points on 32% shooting. The Wolverines controlled the glass with 42 rebounds and forced 15 turnovers in the victory. Roddy Gayle Jr. and Trey McKenney led the Michigan offense in their first game of the season, scoring 17 points apiece. JP Estrella chipped in heavily with 15 points on nine shots. Quinn Costello led the way off the Michigan bench with 13 points on 12 shots in 21 minutes of action.

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UConn vs Michigan Pick

This matchup features two of the better teams in the country Friday night, and that will be evident from the opening tip. Look for UConn to establish itself early and control the tempo from the opening minutes. The Huskies have the depth, talent, and offensive balance necessary to challenge Michigan on both ends of the floor. UConn's defensive pressure and ability to control the glass will be key factors against a talented Wolverines team. Michigan has enough offensive weapons to remain competitive, but the Huskies' depth will wear the Wolverines down over 40 minutes. Take UConn to remain undefeated Friday night with a win and cover in Boston.

  • Pick:

UConn -5.5
  • Secondary:

Over 145.5

Final Score Prediction: UConn Huskies win and cover 86-73.

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