Vanderbilt Commodores vs Wake Forest Demon Deacons Picks & Predictions for Sunday December 21 2025

By: Kim Smith Published 12/21/2025, 03:55 AM ET
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The No. 13 Vanderbilt Commodores travel to Winston-Salem to take on the Wake Forest Demon Deacons on Sunday, December 21, 2025, in a compelling early-afternoon matchup at LJVM Coliseum. Tipoff is set for 1:00 PM ET, with national coverage on The CW Network. This game features an undefeated Vanderbilt team facing a Wake Forest squad that has been strong at home and is playing its best basketball of the season. For more insight and betting angles across today’s slate, be sure to check out free college basketball picks all season long.

Vanderbilt Commodores Preview: Undefeated and Explosive

Vanderbilt enters this matchup a perfect 11–0 overall, including 2–0 on the road, and riding an 11-game winning streak. The Commodores have been one of the most efficient offensive teams in the country, consistently overwhelming opponents with pace, shooting, and depth. Recent wins over Memphis, Saint Mary’s, and VCU highlight how well Vanderbilt has handled quality competition.

Statistically, Vanderbilt has been elite on the offensive end, averaging 93.7 points per game while allowing 72.6. The Commodores shoot 50% from the field, dominate the glass with 40.1 rebounds per game, and share the ball exceptionally well at 19.3 assists per contest. Defensively, they’re disruptive, generating 10.4 steals and 5.0 blocks per game, often turning stops into easy transition points.

The offense is led by Duke Miles, who averages 17.1 points per game while shooting 47.1% from the field and 85.3% from the free-throw line. Miles’ ability to score efficiently without forcing shots fits perfectly into Vanderbilt’s balanced attack, where multiple players can hurt you on any given night.

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Wake Forest Demon Deacons Preview: Dangerous at Home

Wake Forest comes in at 9–3 overall with an impressive 7–1 record at home, making LJVM Coliseum a difficult place for visiting teams. The Demon Deacons are riding a three-game winning streak, highlighted by a dominant 111–73 win over Queens and a solid victory against West Virginia.

From a statistical perspective, Wake Forest averages 85.3 points per game while allowing 72.3, showing a strong balance between offense and defense. The Demon Deacons shoot 46% from the field, pull down 36.5 rebounds per game, and average 16.3 assists. Defensively, they are active with 9.7 steals and 3.9 blocks per game, often disrupting rhythm and forcing turnovers.

Wake Forest is led by Juke Harris, who averages 20.0 points per game on 48.3% shooting. Harris is the clear focal point offensively and has the ability to keep Wake Forest competitive, especially if the game turns into a faster-paced scoring battle.

Key Points to Watch For

  • Undefeated vs Home Strength: Vanderbilt is 11–0, while Wake Forest is 7–1 at home
  • Scoring Output: Commodores average over 8 more points per game
  • Efficiency Edge: Vanderbilt shoots 50% compared to Wake Forest’s 46%
  • Ball Movement: Vanderbilt’s 19.3 assists per game can stress Wake’s defense
  • Star Power: Miles vs Harris could define the scoring flow

Vanderbilt vs Wake Forest Pick

Best Bet: Vanderbilt Commodores to Win

I’m backing Vanderbilt in this spot because their offensive efficiency and depth consistently separate them from good teams. The Commodores score at a significantly higher rate, shoot better, and generate more second-chance and transition opportunities. Even on the road, Vanderbilt has shown composure and balance, which should help neutralize Wake Forest’s home-court edge. Betting on sports and on Wake Forest is easy, but even easier if you use the best sportsbooks. Make sure you know about how the fans are looking on prediction markets for Vanderbilt with the social sportsbooks. Getting the most out of your bets on Vanderbilt vs Wake Forest can be done by using the Fanatics Sportsbook promo code.

Lean Pick: Over the Total

Both teams play at an efficient offensive pace, and Vanderbilt in particular forces opponents to score to keep up. Wake Forest has enough firepower with Harris to contribute, while Vanderbilt’s offense can push the game into a higher-scoring range.

Vanderbilt’s depth and efficiency should gradually wear down Wake Forest, especially in the second half when the Commodores have consistently pulled away from opponents.

Final Score Prediction

Vanderbilt Commodores 90, Wake Forest Demon Deacons 81

Vanderbilt remains undefeated, handling a tough road environment and reinforcing its status as one of the most dangerous teams in the country.

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