Arizona State vs Colorado Picks and Prediction for Saturday November 22 2025

By: Eddie Kline Updated 11/22/2025, 01:23 AM ET

Arizona State Preview

Folsom Field will play host to a Saturday night college football clash between the Arizona State Sun Devils and the Colorado Buffaloes. Confident betting starts with the right insights—check out our college football predictions now. The Sun Devils (7-3) have won five of their first seven Big 12 Conference games and are scoring 24.7 points per contest. On Saturday, Arizona State erupted for 22 points during the second quarter and held on for a 25-23 home victory versus West Virginia.

Arizona State QB Jeff Sims completed 19 of 28 passes for 207 yards and three touchdowns. Sims added a game-high 81 rushing yards on 17 carries. WR Derek Eusebio caught six passes for 74 yards and a 19-yard touchdown reception. LB Jordan Crook recorded 14 tackles (10 solo) for the Sun Devils. Make sure you know about how the fans are looking on prediction markets for Arizona State with the Thrillz promo code.

Colorado Preview

The Colorado Buffaloes have dropped six of their first seven Big 12 Conference games and could be looking for a new head coach in the offseason. The Buffaloes (3-7) are in the midst of a three-game losing streak and have surrendered an alarming 144 points over that stretch. Last time out, Colorado converted just 5 of 17 third-down attempts during a 29-22 road loss against West Virginia.

Freshman QB Julian Lewis got the starting nod from head coach Deion Sanders and threw for two touchdowns. Omarion Miller hauled in six receptions for a game-high 131 yards and a score. LB Jeremiah Brown added 11 tackles for the Buffaloes. Make the most of your bets on Colorado by using the sportsbook promos.

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Arizona State vs Colorado Pick

Arizona State QB Sam Leavitt has been lost for the season with an undisclosed injury and is a potential transfer candidate. Head coach Kenny Dillingham has expressed his commitment to lead this program in the future, while Colorado head coach Deion Sanders appears to have one foot out the door. Take the Sun Devils to win and cover on the road. Final Score Prediction, Arizona State Sun Devils win 31-17. Make sure when you place your Arizona State vs Colorado bet you are using the bet365 bonus code.

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