Arizona State vs Mississippi State Picks and Predictions for Saturday September 6 2025

By: Jeremy O'Quinn Published 09/01/2025, 08:16 PM ET
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Arizona State Preview

The Arizona State Sun Devils are heading to Davis Wade Stadium in week two of college football, where they will face the Mississippi State Bulldogs. Get the rest of our free NCAAF picks here! The Arizona State Sun Devils sit 1-0, ranked 11th in the Big 12. ASU comes into Week 2 riding a 38–19 victory over Northern Arizona in Week 1. Sun Devils’ quarterback Sam Leavitt was impressive on opening day, completing 25 of 39 passes for 257 yards and 2 touchdowns, while also rushing for 73 yards and 2 touchdowns. ASU’s top offensive option, Jordyn Tyson hauled in 12 passes for 141 yards and 2 touchdowns.

Mississippi State Preview

The Mississippi State Bulldogs currently sit 1-0 in the SEC. The Bulldogs opened their season on the road with a 41–20 victory over Southern Miss. Mississippi State quarterback Blake Shapen was efficient, going 26 of 34 for 270 yards, throwing 1 touchdown and 1 interception. On the ground, Davon Booth led the rush with 79 yards and 1 touchdown, while Brenen Thompson led all Arizona receivers with 7 catches for 92 yards.

Mississippi State vs Arizona State Pick

Sam Leavitt and the Sun Devils were extremely impressive in week 1 against Northern Arizona, while Mississippi State also comes off a strong week 1 performance. Leavitt will be the difference maker in this game, leading Arizona State to cover the -7.5 spread. Final score prediction, Sun Devils win 33-17.

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