BYU at Colorado Picks and Prediction for Saturday, September 27, 2025

By: Garrett Beaverson Updated 09/27/2025, 01:13 AM ET
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The BYU Cougars (3-0) will head into Big 12 play with a road trip to Boulder to take on the Colorado Buffaloes (2-2) at Folsom Field. Kickoff is set for 10:15 PM EDT / 8:15 PM local (Mountain Time). BYU is riding momentum from a convincing win over East Carolina, and Colorado will look to bounce back after mixed results in non-conference and Big 12 action. This will be BYU’s Big 12 opener. Get the edge this weekend with our free college football picks backed by data and trends.

BYU Cougars Analysis

BYU enters this game unbeaten and with rising confidence. Their defense has made some splash plays, and the offense has been productive enough, especially in critical moments. Key areas of strength: takeaway ability, balanced offense, and improving performance in third-down / red zone situations.

Key Team Stats & Player Metrics

From their cumulative stats through three games:

  • BYU’s passing game: 94 pass attempts, 52 completions, 4 passing TDs, 0 interceptions.

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  • Passing yards per game: ~161 yards per game in the passing attack, with average yards per attempt in the high 5-low 6 range.

  • Rushing attack: They’ve averaged 312.5 rushing yards per game along with strong yards per carry when they commit to ground game.

  • Scoring margin and offensive prowess: BYU has been good offensively. In the betting report, they average ~43.3 points scored vs opponents’ ~5.3.

Colorado Buffaloes Analysis

Colorado has had an up-and-down start, with wins showing promise but also losses exposing weaknesses. Under pressure now in Big 12 play, especially at home. If their offense can click, they have playmakers; if not, BYU could take over.

Key Team Stats & Player Metrics

  • Colorado’s record: 2-2 overall, 0-1 in Big 12 after their loss at Houston.

  • In their most recent game (vs Wyoming), QB Kaidon Salter threw for ~304 yards and also rushed for about 86 yards.

  • Offense per game: ~233.5 total yards/game, with passing yards around 140-150/game and rush yardage less stable.

  • Defense: Colorado allows a fair amount of yardage, especially in passing and in big plays. Their scoring defense and third-down conversion defense need work.

Standout Players and Key Injuries

BYU:

  • Freshman QB Bear Bachmeier — has shown poise, good decision-making, minimal turnovers.

  • Defensive playmakers (e.g. Evan Johnson, who had a goal-line interception and pick-6 vs ECU) bolstering BYU’s turnover game.

  • Rushing backs: BYU’s run game has been productive enough to keep defenses honest.

Colorado:

  • Kaidon Salter — the most important player for Colorado on offense; his ability to extend plays and run adds a dangerous dimension.

  • Key receivers in Colorado (names not fully detailed in sources) who can stretch the field; if Salter connects deep, that could open things up.

  • Colorado’s defense: needs to make stops, especially in 3rd down and red zone; they need to limit BYU’s big plays and take advantage of any mistakes.

Colorado vs BYU Prediction Reasoning

Putting this together, BYU appears to have the edge. They’re more consistent so far, have momentum, and are entering with confidence. Colorado has potential, especially at home, but their inconsistency and tendency to allow big plays make them vulnerable to a well-executed game from BYU. Colorado seems like a team that will have trouble with good conference opponents all season.

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Final Score Projection: BYU 31, Colorado 20

Best Picks

  • BYU ML
  • Over up to 51 total points
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