Clemson at South Carolina — Picks & Prediction for Saturday, November 29, 2025

By: Garrett Beaverson Published 11/24/2025, 10:55 PM ET
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The Clemson Tigers make the short trip to Columbia to face their arch-rival, the South Carolina Gamecocks, on Saturday, November 29, 2025. Get in on the action with our free NCAAF picks.

Clemson Tigers Analysis

Clemson enters this showdown under pressure. They sit at 6–5 as they head into the season finale.

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Make sure you know about how the fans are looking on prediction markets for South Carolina with the social sportsbooks.

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  • Offense: They average about 399.2 yards per game. Their game log shows a balanced attack, with 278.3 pass yards and 120.9 rushing yards per game.

  • Scoring: Clemson puts up 27.1 PPG.

  • Defense: They allow 22.1 PPG, giving them a positive scoring margin.

Strengths:

  • Passing game: Their aerial attack is strong, and they can stretch the field.

  • Big-game experience: Clemson has played in high-pressure rivalry games before; they know what’s at stake.

  • Balanced offense: The mix of pass and run gives them flexibility to change pace.

Weaknesses:

  • Inconsistency in the run game: Their rushing numbers don’t dominate, which could be a problem if they fall behind.

  • Turnover risk: In a rivalry with high emotion, careless mistakes could be costly.

  • Motivation variance: With postseason hopes on the line, pressure may impact execution.

South Carolina Gamecocks Analysis

South Carolina comes in with a sub-.500 season, but as the home team in this rivalry, they’ll be highly motivated.

  • Offense: They average 303.5 yards per game, with 200.7 passing and 102.8 rushing.

  • Scoring: Just 20.7 PPG, per their season stats.

  • Defense: They allow 23.0 PPG, which means they’ve traded some points but may try to make this a low-tempo game.

Strengths:

  • Home-field energy: Rivalry games in Columbia are always fiery — South Carolina can use the crowd.

  • Passing ability: While not elite, they have enough in the air to challenge Clemson’s secondary.

  • Desperation factor: With a disappointing season, this game could mean everything for their bowl hopes or program momentum.

Weaknesses:

  • Inconsistent scoring: Their low PPG average suggests they may struggle to keep pace if Clemson gets going.

  • Defensive lapses: Allowing over 23 PPG could be problematic if Clemson’s offense capitalizes.

  • Limited ground game: With just over 100 rushing yards per game, their offense may stall without explosive plays.

Standout Players & Key Matchups

  • Clemson:

    • Cade Klubnik — his decisions will matter under pressure.

    • Adam Randall — their primary running threat, important if Clemson leans on the ground.

  • South Carolina:

    • LaNorris Sellers — their signal-caller, who must keep plays alive and limit turnovers.

Prediction Reasoning

Both teams have been weak on offense and inconsistent throughout the season. As the home team with the better QB, we will take South Carolina as more of a fade on the Tigers.

Final Score Projection: Clemson 21, South Carolina 24

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