Colorado State vs UTSA Picks and Prediction for Saturday, September 26, 2026

By: David Anicetti Published 09/22/2026, 09:19 PM ET

The Colorado State Rams visit the UTSA Roadrunners on Saturday, September 26, at the Alamodome in San Antonio, with the opening kickoff scheduled for 12:00 PM ET on ESPNU. The Colorado State Rams are 2-1 overall and have not opened play in the Pac-12 after a 41-23 loss to BYU. The UTSA Roadrunners are also 2-1 overall and have not opened their schedule in the American Conference after losing 30-6 at Texas. Check out our free NCAAF picks.

Colorado State Rams Preview

Colorado State is averaging 38.7 points through three games and has produced 281.3 passing yards and 177.3 rushing yards per game. Hauss Hejny has completed 47 of 73 passes for 619 yards, 10 touchdowns, and one interception while adding 128 rushing yards and a score. Mel Brown leads the Rams with 256 rushing yards and two touchdowns on only 26 carries. RJ Vick has 175 receiving yards and a team-high four touchdowns, while Cedric Ross has 178 yards and two scores.

The Rams are allowing 26 points per game after giving up 13 to Wyoming, 24 to Southern Utah and 41 to BYU. Colorado State has five sacks and seven interceptions through three games. CJ Blocker leads the secondary with three interceptions, while Oumar Diomande has two. Tre'Shawn Moore leads the defense with 25 tackles and has added one sack, one forced fumble, and one recovery. Elijah Brown has 1.5 sacks, and the defense has recovered three fumbles.

Injuries: No injuries to report.

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UTSA Roadrunners Preview

UTSA is averaging 27.3 points through three games after scoring just six in its latest loss at Texas. Owen McCown has completed 64 of 92 passes for 559 yards, four touchdowns and one interception. The Roadrunners have rushed for 464 yards, averaging 154.7 per game and 5.5 yards per carry. Will Henderson III leads the backfield with 219 yards and a touchdown, while A'Marion Peterson has 112 yards and two scores. DJ Allen Jr. leads UTSA with 155 receiving yards.

The Roadrunners are allowing 24 points per game, with opponents scoring 16, 26 and 30 points across their first three contests. UTSA has recorded only two sacks but has four interceptions and two fumble recoveries. Brandon Tucker leads the defense with 29 tackles and one sack. Darion White and James Walley Jr. have 17 tackles each. Cameron Upshaw Jr., Zach Morris, Nate Robinson Jr. and Drenon Fite III have each recorded an interception.

Injuries: No injuries to report.

Colorado State vs UTSA Prediction

Colorado State brings the more productive offense into San Antonio, with the Rams averaging 11.3 more points per game and getting strong production from Hejny through the air. The Rams have also created seven interceptions, an important matchup against a UTSA offense coming off a six-point performance. UTSA has a productive rushing attack and home field advantage, but Colorado State has averaged 6.0 yards per carry and has multiple ways to create big gains. The Rams can keep this game close enough to cover 12.5 points, while UTSA has the advantage at home in a tight finish. Final Score Prediction: UTSA Roadrunners win but Colorado State covers the spread, 34-27.

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  • Colorado State Rams +12.5 
  • Over 57.5
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