Colorado vs TCU Picks and Prediction for Saturday, October 4, 2025

By: Cameron Ross Updated 10/03/2025, 11:05 PM ET
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Colorado vs TCU Information

The Colorado Buffaloes return to the road this week with a game in Amon G. Carter Stadium against the TCU Horned Frogs at 7:30 PM. Colorado has just two wins on the year coming into this week, following a narrow loss against BYU a week ago after blowing a 14-point lead. The TCU Horned Frogs have played well this season, with three wins and one loss overall after a three-point road loss to Arizona State in their last outing. Confident betting starts with the right insightsβ€”check out our college football predictions now.

Colorado Preview

The Colorado Buffaloes have been mediocre on the offensive side of the ball this season, averaging 26.4 points per game overall, but have averaged just 20.3 points per game during their three losses. Defensively, Colorado has been mediocre, allowing 22.8 points per game this year. Kaidon Salter leads the Colorado offense this season with 684 yards and five scores on 59 completions. Ryan Staub has completed 26 passes for 362 yards and three touchdowns. Michah Welch is the top ball carrier on the team with 210 yards and one touchdown on 40 carries. Joseph Williams is the top receiver on the roster with 14 catches for 220 yards and two touchdowns.

TCU Preview

Defensively, TCU has been stout this season, holding opponents to 21.5 points per game, but it gave up 27 points in its lone loss of the year. Offensively, TCU has been strong, averaging 37.25 points per game through four games played. Josh Hoover leads TCU this season with 1243 yards and 11 touchdowns on 90 completions. Kevorian Barnes leads the team with 21 carries for 156 yards and 1 touchdown, and Trent Battle has added 21 carries for 138 yards and three scores. Eric McAllister is the top receiver on the roster with 13 catches for 320 yards and three scores.

Colorado vs TCU Prediction

TCU is the better team in this matchup and will overwhelm a struggling Colorado team this week. Look for the Horned Frogs to bounce back on their home field this week as they get to win and cover at home. Take the Horned Frogs to get their fourth victory of the season in blowout fashion as they roll past Colorado. Final Score Prediction, TCU Horned Frogs win and cover 45-13.

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Best Picks:

  • TCU Horned Frogs -13.5
  • Over 57.5
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