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Eastern Michigan vs Kentucky Picks and Predictions for Saturday, September 13, 2025

By: Jake Allman Published 09/07/2025, 11:45 PM ET

Eastern Michigan vs Kentucky Game Info

Eastern Michigan heads to Kroger Field on Saturday evening looking for its first win of the season when it faces Kentucky. The Eagles are 0-2 after dropping games to Texas State and LIU, while the Wildcats sit at 1-1 following a close win over Toledo and a seven-point loss to Ole Miss. Kickoff is set for 5:30 PM ET on ESPNU in Lexington, KY. Rivalry week? Bowl season? Our college football predictions keep you ahead.

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Eastern Michigan Preview

Eastern Michigan has had issues closing games early in the year, allowing 80 points across the first two contests. Quarterback Noah Kim has been a bright spot, throwing for 437 yards and three touchdowns on a strong 41-for-63 completion rate. Running back Dontae McMillan has added 136 yards and a score on just 17 carries, showing efficiency when given opportunities. Wideout Terry Lockett Jr. has been Kim’s top target with 13 catches for 140 yards, providing some consistency in the passing game.

The Eagles have struggled to slow down opposing offenses, giving up 52 points to Texas State and another 28 to LIU. Marco Patierno has led the tackling effort with 12 stops, but the lack of pressure on quarterbacks has hurt the Eagles' chances of getting off the field. To stay competitive against Kentucky, Eastern Michigan will need to find ways to generate turnovers and sustain longer drives to keep its defense fresh.

Kentucky Preview

Kentucky enters at 1-1, showing both promise and inconsistency. Quarterback Zach Calzada has managed 234 yards through the air but is still searching for his first touchdown, completing just 25 of 53 passes. The ground game has been more effective, with Dante Dowdell carrying 28 times for 185 yards and a touchdown. Kentucky leans on this physical rushing attack to control tempo and wear down opponents.

The Wildcats are anchored by linebacker Alex Afari Jr., who leads the team with 23 tackles. Kentucky allowed 30 points against Ole Miss but held Toledo to just 16 in the opener, a sign they can adjust well depending on the matchup. With home-field advantage, the ability to establish the run and win battles at the line of scrimmage gives them a clear edge against an Eastern Michigan team that has been vulnerable in both phases.

Eastern Michigan vs Kentucky Prediction: Kentucky 34, Eastern Michigan 17

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Best Picks:

  • Kentucky -6.5
  • Over 54.5 total points
  • Eastern Michigan team total under 21.5
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