Florida State vs Virginia Picks and Predictions for Friday, September 26, 2025

By: David Anicetti Published 09/21/2025, 01:47 PM ET
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The Florida State Seminoles visit Scott Stadium to face the Virginia Cavaliers on Friday, September 26, 2025, at 7:00 p.m. ET on ESPN. Florida State is 3–0 after wins over Alabama (31–17), Texas A&M–Commerce (77–3), and Kent State (66–10). Virginia is 3–1 after beating Coastal Carolina (48–7), losing at NC State (35–31), and topping William & Mary (55–16) and Stanford (48–20). Build your bankroll, use our college football predictions.

Florida State Preview

Quarterback Tommy Castellanos has had big plays through the air. Castellanos is 27 of 38 for 584 yards with 3 touchdowns and 1 interception. Duce Robinson is the main target with 8 catches for 199 yards and 2 touchdown receptions, including an 82-yard catch. The run game is solid: Micahi Danzy (173 yards, 3 TDs on just five carries), Castellanos (139 yards, 3 TDs), and Samuel Singleton Jr. (168 yards, 3 TDs).

The defense has been tough against the run and pass. Earl Little Jr. leads with 17 tackles and an interception return of 48 yards. Florida State 9.0 sacks and steady pass breakups, with Mandrell Desir and Daniel Lyons among the best pass defenders. Special teams have been very good with 23-for-23 on extra points and 2-for-2 on field goals.

Virginia Preview

Quarterback Chandler Morris is off to a steady start: 1,050 yards, 8 touchdowns, and 1 interception. The Cavaliers' running game performed very well. J’Mari Taylor leads the way with 298 yards and 6 touchdowns, while Harrison Waylee has 214 yards and 4 touchdowns, highlighted by a 97-yard rushing touchdown. Through the air, Trell Harris leads with 14 catches for 221 yards and three touchdown receptions.

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Defensively, linebacker Landon Danley tops Virginia with 25 tackles. The Cavaliers have recorded 6.0 sacks and two interceptions. The group has held up in the red zone and has performed well in short-yardage situations. Kicking has been solid, with Will Bettridge making 7 of 10 FGs and 23-for-23 extra points.

Florida State vs Virginia Prediction

Florida State has a much better offense that can score from anywhere on the field. Virginia’s ground game can control the clock, but FSU’s defense will take that away from the Cavaliers. The Seminoles are not only explosive on offense, but have a defense that can stop the run and defend against the pass. Final Score Prediction: Florida State Seminoles win and cover ATS 35-23.

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