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Florida vs LSU Picks and Predictions for Saturday, September 13, 2025

By: Jake Allman Published 09/07/2025, 11:49 PM ET

Florida vs LSU Game Information

Two SEC rivals collide in Baton Rouge on Saturday night when Florida visits LSU at Tiger Stadium. The Gators come in at 1-1 after an opening win over LIU, followed by a disappointing 18-16 loss to USF. LSU is off to a 2-0 start with victories over Clemson and Louisiana Tech. Kickoff is set for 5:30 PM ET on ABC in what should be a physical conference battle. Our college football predictions keep you ahead.

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Florida Preview

Florida has leaned on freshman quarterback DJ Lagway, who has been efficient through two games with 342 passing yards and four touchdowns against just one interception. Running back Jadan Baugh leads the backfield with 197 yards on 27 carries and a score, giving the Gators balance in the offense. Vernell Brown III has emerged as the top receiving option with 135 yards on eight catches, giving Lagway a reliable downfield threat.

The Gators’ defense kept them in the game against USF, holding the Bulls to just 18 points. Linebacker Jaden Robinson has been a key figure with 13 tackles, while Tyreak Sapp has contributed pressure up front. Florida has shown that it can limit explosive plays, but going on the road to Tiger Stadium presents a much tougher test. They will need to avoid turnovers and sustain long drives to keep LSU’s playmakers on the sideline.

LSU Preview

LSU has opened with two hard-fought wins, behind quarterback Garrett Nussmeier. The signal caller has already attempted 79 passes, completing 54 for 469 yards, two touchdowns, and one interception. His top target has been Aaron Anderson, who leads the Tigers with 172 yards on 14 receptions. On the ground, Caden Durham has given LSU toughness in short-yardage situations with 103 yards and two touchdowns.

The Tigers’ defense has been a difference-maker, holding Clemson to just 10 points and keeping Louisiana Tech out of rhythm in a 23-7 win. Linebacker West Weeks leads the team with 15 tackles, while Harold Perkins Jr. continues to be disruptive in the front seven. With depth and speed on both sides of the ball, LSU has the tools to control tempo at home and put pressure on a young Florida quarterback.

Prediction: LSU 27, Florida 20

Best Picks for Florida vs LSU:

  • Florida +6.5
  • Under 54.5 total points
  • Aaron Anderson over receiving yards prop
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