Iowa State vs Cincinnati Picks and Prediction for Saturday, October 4, 2025

By: Cameron Ross Updated 10/03/2025, 11:06 PM ET
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Iowa State vs Cincinnati Information

The Iowa State Cyclones will be back on the road this week with a game in Nippert Stadium against the Cincinnati Bearcats. Iowa State is ranked inside the top 25 undefeated through five games played following a 25-point blowout home win against Arizona last week. The Cincinnati Bearcats will be back on their home field this week, three wins and one loss on the year, riding a three-game winning streak after a narrow 3-point road victory against Kansas last week.Β Don’t guess on Saturdayβ€”grab the smartest plays with our free college football predictions.

Iowa State Preview

The Iowa State Cyclones have been a complete team on both sides of the ball this season, averaging 31.6 points per game offensively. Defensively, Iowa State is allowing just 14.2 points per game through five games played. Rocco Becht leads the Iowa State offense this season with 1103 yards and seven scores on 79 completions. Carson Hansen leads the way on the ground for the Cyclones with 315 yards and two touchdowns on 73 carries. Brett Eskiidsen is the top receiver on the team with 216 yards and one touchdown on 10 receptions.

Cincinnati Preview

The Cincinnati Bearcats have averaged 39.5 points per game this season but scored only 17 points in their opening week loss to Nebraska. Defensively, Cincinnati has been stout, holding opponents to an average of 18.5 points per game overall. Brendan Sorsby leads the Cincinnati offense this season with 1043 yards and 10 scores on 74 completions to go along with the team-leading 227 yards and four touchdowns on 35 carries. Tawee Walker has added a second-best 224 yards and three touchdowns on 42 carries. Cyrus Allen leads the team with 273 yards and five touchdowns on 23 grabs this season.

Iowa State vs Cincinnati Prediction

Iowa State is ranked coming into this matchup, pushing towards a potential playoff berth. Look for the Cyclones to do the work on both sides of the ball against a good Cincinnati team this week. Take Iowa State to stay undefeated as they pull off the win and cover on the road against the Bearcats this week. Final Score Prediction, Iowa State Bearcats win and cover 38-21.

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Best Picks:

  • Iowa State Cyclones +1.5
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