Jacksonville State vs Southern Miss Picks and Prediction for Saturday, September 27, 2025

By: Cameron Ross Updated 09/27/2025, 01:16 AM ET
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Jacksonville State vs Southern Miss   Information

The Jacksonville State Gamecocks will be back on the road this week with a game in Mississippi against the Southern Miss Golden Eagles inside M.M. Roberts Stadium at 7:00 PM. Jacksonville State has split its first two games of the year coming into this week, following a 35-point victory against Murray State at home. The Southern Miss Golden Eagles return home this week with two wins and two losses following a 10-point road loss to Louisiana Tech a week ago. Discover which teams the pros are backing with our daily college football picks.

Jacksonville State Preview

The Jacksonville State offense has been the team's biggest strength this season as the Gamecocks is averaging 30.75 points per game overall. Defensively, Jacksonville State said just enough, holding opponents to 23 points per game through four games played. Gavin Wimsatt leads the Jacksonville State offense this season with 557 yards and two scores on 54 completions. Cam Cook is the top ball carrier on the roster this season with 537 yards and four scores on 89 carries. Brock Rechsteiner leads the team with 13 catches for 191 yards and two scores.

Southern Miss Preview

Offensively, Southern Miss has scored every 28.25 points per game through three games played. Defensively, Southern Miss has had some troubles, giving up 26.5 points per game and allowing thirty points in their most recent loss. Braylon Braxton has orchestrated this other miss offense this season, leading the team with 1084 yards and 9 scores on 96 completions to go along with the team high 128 yards on 39 carries. Jeffery Pittman has chipped in heavily on the ground with 25 carries for 126 yards and two scores. Carl Chester leads the team with 13 catches for 211 yards this year.

Jacksonville State vs Southern Miss Prediction

Jacksonville State is a better team on both sides of the ball and will do the work this week. Look for the Gamecocks to come out early against a mediocre Southern Miss team, leading to the victory. Take Jacksonville State this week to get the winning cover on the road as they pick up their third victory of the season. Final Score Prediction, Jacksonville State Gamecocks win and cover 31-17.

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Best Picks:                

  • Jacksonville State Gamecocks +3.5
  • Under 57
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