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Kansas State vs Arizona Picks and Predictions for Friday, September 12, 2025

By: David Anicetti Published 09/07/2025, 10:51 PM ET

The Kansas State Wildcats visit Arizona Stadium in Tucson, Arizona, on Friday to play the Arizona Wildcats with FOX carrying the prime-time Big 12 clash at 10:00 PM ET. The Wildcats lost to Army after beating North Dakota, while Arizona has cruised past Weber State and Hawaii. Keep up to date with all the College Football action, with our College Football predictions.

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Kansas State Preview

Kansas State’s offense leans on dual-threat QB Avery Johnson, who has thrown for 763 yards with six touchdowns and one interception. The Kansas State running game is led by Joe Jackson, who has rushed for 136 yards but has not yet found the end zone. Jayce Brown leads all receivers with 216 yards and a pair of touchdown receptions. The Wildcats have played three one-score games dating back to Week Zero

On the other side of the ball, Kansas State is led in tackles by linebacker Austin Romaine with 28, while linebacker Desmond Purnell is second with 17. Kansas State has made seven quarterback sacks through its first three games of the season, but has not yet intercepted a pass. The Wildcats need to come up big against a tough Arizona offense and must play well against both the run and the passing game of the Wildcats.

Arizona Preview

The Arizona offense is powered by quarterback Noah Fifita, who has completed 66.7% of his passes for 534 yards and six touchdowns. Fifita has not yet been picked off. The Arizona Ground game is led by Quincy Craig with 156 yards rushing and one touchdown, while through the air, Javin Whatley leads all receivers with 206 yards and two touchdown receptions. Arizona has scored four touchdowns on the ground and six through the air.

Arizona's defense is led by linebacker Taye Brown and defensive back Dalton Johnson, who both have 12 tackles, while defensive back Genesis Smith has made 11 tackles. Arizona has made seven quarterback sacks, and the Wildcats have made five interceptions. Arizona's defense is a key component of its success and will create problems for Kansas State on each possession.

Kansas State vs Arizona Prediction

Arizona’s balance on offense, its pass rush and interception rate in the secondary will be too much for Kansas State. Playing at home in 90-plus degree temperature will also favor the Wildcats. Final Score Prediction: Arizona Wildcats win and cover ATS 33-17.

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