Kansas vs Missouri Picks and Prediction for Saturday September 6 2025

By: Cameron Ross Published 09/02/2025, 11:25 PM ET

Kansas Preview

The Kansas Jayhawks roll into Columbia, MO, this week for a matchup against the Missouri Tigers. Kansas is 2-0 on the year coming into this matchup following a 39-point victory a week ago. Offensively, Kansas was a smoke show a week ago, scoring 46 points after 29 came in the first half on 631 total yards. The Jayhawks' defense did the job as well, giving up to seven points on 143 total yards and allowing only two third-down conversions. For other college football action, see our College Football Picks.

Jalon Daniels has been the offensive leader for Kansas this season with 456 yards and seven touchdowns on 36 completions through two games. Daniel Hishaw Jr is the top ball carrier with 158 yards and one score on 27 carries. Emmanuel Henerson Jr leads the team with 154 yards and two scores on 9 catches. Cam Pickett has chipped in eight catches for 106 yards and three scores this season through two games played.

Missouri Preview

The Missouri Tigers stay on their home field this week undefeated through one game following a 55-point victory against Central Arkansas to open the season. Defensively, Missouri was a far better team a week ago, giving up just six points on 227 total yards and forcing 2 turnovers in the game. Offensively, Missouri was just as strong, scoring 61 points after 35 in the second half on 560 total yards.

Beau Pribula led the way for the Missouri offense a week ago, completing 23 passes for 283 yards and two scores. Matt Zollers came on to complete three passes for 58 yards and one touchdown. Ahmad Hardy was the top ball carrier on the roster with 100 yards and one touchdown on 10 carries. Quarterback Beau Pribula chipped in 10 carries for 65 yards and two scores on the ground. Marquis Johnson led the team with 130 4 yards and one touchdown on five receptions.

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Kansas vs Missouri Pick

Both teams come into this matchup undefeated, but Kansas is playing the better football. The Jayhawks have already played two games and will use that experience this week. Take Kansas to continue to play well enough as they do the job to cover the number and pull off the outright win as the underdog in Missouri. Final Score Prediction, Kansas Jayhawks win and cover 34-28.

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