Kentucky vs South Carolina Picks and Prediction for Saturday September 27 2025

By: Eddie Kline Updated 09/27/2025, 01:25 AM ET

Kentucky Preview

SEC Conference foes will square off on Saturday night, when the Kentucky Wildcats battle the South Carolina Gamecocks from Williams-Brice Stadium. Saturday success begins with free college football picks you can rely on. The Wildcats (2-1) are looking to rebound from a disappointing four-win season and are scoring 31.7 points per game. Last time out, Kentucky scored at least ten points in each quarter on their way to a 48-23 home victory versus Eastern Michigan.

Kentucky raced out to a 14-0 first quarter lead on a pair of touchdowns from RB Seth McGowan (104 rush yds). Senior TE Josh Kattus hauled in three passes for 61 yards and a score. The Wildcats rushed for 252 yards on 46 carried and converted 5 of 11 third down attempts.

South Carolina Preview

The South Carolina Gamecocks finished the 2024 campaign as one of the hottest teams in college football, but have dropped their first two SEC Conference games this season. The Gamecocks (2-2) rank last in the conference in total offense and are averaging just 22.3 points per contest. On Saturday, South Carolina allowed Missouri to score the final 11 points during a 29-20 road loss.

South Carolina built a 14-12 halftime advantage and stayed ahead entering the fourth quarter on two William Joyce field goals. LaNorris Sellers completed 18 of 28 passes for 302 yards and two scores. The Gamecocks were limited to negative nine rushing yards on 22 attempts.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Kentucky vs South Carolina Pick

Kentucky got thumped by visiting South Carolina last year by a 31-6 final score. The Gamecocks have lost plenty of talent from last season’s squad and the Wildcats are coming off a bye. Take Kentucky to get revenge and pull off the upset on the road. Final Score Prediction, Kentucky Wildcats win 24-23.

Betting on College Football?

Bet with other College Football fans at the best sportsbooks
Sign up today and get started with the latest college football sportsbook promos

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).

Min. Deposit $5

Odds Requirements -500

Cashable No

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 7/19/26 at 11:59 PM ET. Sponsored by DK.