LSU vs Alabama Picks & Prediction for Saturday, November 8, 2025

By: Thomas Pemberton Updated 11/08/2025, 01:44 AM ET

The LSU Tigers travel to Tuscaloosa this weekend to take on the Alabama Crimson Tide. Kickoff is scheduled for 7:30 PM est at Bryant-Denny Stadium. Alabama is a -11.5 home favorite and the over/under is set at 49.5 points. Looking to cash in this weekend? Start with our trusted college football picks.

LSU Tigers Preview

The LSU Tigers are 5-3 on the season. LSU is 1-2 on the road and they are riding a two game losing streak. The Tigers lost to Texas A&M 49-25 in their last game played. QB Garrett Nussmeier threw for 168 yards with a touchdown. Nussmeier has 12 touchdowns and 5 interceptions on the season. WR Barion Brown leads the Tigers with 36 receptions. While running back Caden Durham has 378 rushing yards and 2 touchdowns on the season. The LSU Tigers are averaging 25.5 points scored per game.

Alabama Crimson Tide Preview

The Alabama Crimson Tide are 7-1 on the season. Alabama is a perfect 4-0 on their home field and they are riding a seven game win streak. The Crimson Tide beat South Carolina 29-22 on the road in their last game. QB Ty Simpson threw for 253 yards with 2 touchdowns. Simpson has 20 touchdowns and 1 interception on the season. WR Germie Bernard leads the Crimson Tide with 38 catches for 526 yards and 6 touchdowns. Running back Jam Miller has 308 rushing yards on 80 carries.

LSU vs Alabama Picks & Prediction

The LSU Tigers are 3-5 against the spread. While Alabama has covered the number in five games this season. Alabama beat LSU last season 42-13. Alabama hasn't allowed more than 24 points since Week 1. Lay the points with the Crimson Tide as LSU will continue to struggle.

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  • Final Score Prediction: Alabama Crimson Tide win 38-20 and cover ATS.

LSU vs Alabama Best Free Picks

  • Alabama Crimson Tide -11.5
  • OVER 49.5

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