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LSU vs Oklahoma Picks and Predictions for Saturday, November 29, 2025

By: Cameron Ross Updated 11/25/2025, 12:52 AM ET

LSU vs Oklahoma Information

The LSU Tigers will be on the road this week, playing the Oklahoma Memorial Sooners at 3:30 PM in Memorial Stadium. LSU has seven wins and four losses coming into this week, having won two in a row after a three-point victory against Western Kentucky. The Oklahoma Sooners are the 8th-ranked team in the nation, with 9 wins and 2 losses, having won the last 5, including 3 in a row, after an 11-point home victory against Missouri last week. Stay in the news with our College Football Picks.

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LSU Preview

Garrett Nussmeier leads the LSU offense this season with 1927 yards and 12 touchdowns on 194 completions. Kaden Durham is the top ball player on the team with 463 yards and three scores on 100 carries, while Harlem Berry has added 423 yards and two scores on 87 carries. Barion Brown leads the team with 486 yards and one touchdown on 49 receptions. Trey’Dez Green has added 323 yards and five scores on 28 catches this season. Betting on sports and on LSU is easy, but even easier if you use the best sportsbooks.

Oklahoma Preview

John Mateer leads Oklahoma this season with 2260 yards and 10 touchdowns on 198 completions to go along with 389 yards and seven touchdowns on 122 carries. Xavier Robinson leads all ball carriers for Oklahoma with 408 yards and four scores on 74 carries. Tory Blaylock has added 98 carries for 402 yards and four scores. Isiaiah Sategna III leads the team with 827 yards and six touchdowns on 56 receptions. Make sure you know about how the fans are looking on prediction markets for Oklahoma with the social sportsbooks.

LSU vs Oklahoma   Prediction

This game is a must-have for Oklahoma as they try to punch their ticket to the College Football Playoff. Oklahoma is ranked 10th and must continue its winning ways convincingly this week. Look for the Sooners to defend home field, with a resounding win and cover this week against LSU to close the regular season. Final Score Prediction, Oklahoma Sooners win and cover 27-14. Getting the most out of your bets on LSU vs Oklahoma can be done by using the Fanatics Sportsbook promo code.

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Best Picks:

  • Oklahoma Sooners -10.5
  • Over 36.5
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