Marshall vs. Louisiana Picks and Prediction for Saturday, September 27, 2025

By: Thomas Pemberton Updated 09/27/2025, 01:17 AM ET

The Louisiana Ragin' Cajuns welcome in the Marshall Thundering Herd on Saturday. The Ragin' Cajuns are a -2.5 home favorite and the total is set at 46.5. Marshall is riding a two game win streak. While Louisiana has lost two straight games. Discover which teams the pros are backing with our daily college football picks.

Louisiana Ragin' Cajuns Preview

The Louisiana Ragin' Cajuns are 1-3 on the season with a 1-1 home field record. Louisiana carries a 1-3 against the spread record. The Ragin' Cajuns have allowed 86 total points during their two game losing streak. Louisiana lost their last game 34-31 to Eastern Michigan. QB Daniel Beale threw for 222 yards and 2 interceptions in the loss. Beale has just one touchdown on the season. The Louisiana Ragin' Cajuns have two running backs with 3 rushing touchdowns each. Bill Davis has 269 rushing yards. While Zylan Perry has 336 rushing yards on the season.

Marshall Thundering Herd Preview

The Marshall Thundering Herd are hoping to find their third straight win of the season. Marshall has scored at least 38 points in two straight games. The Thundering Herd beat Middle Tennessee in their last game 42-28. QB Carlos Del Rio-Wilson threw for 261 yards with 4 passing touchdowns in the win. Del Rio-Wilson has 6 passing touchdowns on the season with no interceptions. WR Demarcus Lacey leads Marshall on the season with 10 catches. Lacey has 129 receiving yards and a touchdown catch. Del Rio-Wilson also leads the Thundering Herd with 29 rushing attempts on the season. Del Rio-Wilson has rushed for 2 touchdowns as well.

Louisiana vs Marshall Picks & Prediction

The Marshall Thundering Herd beat up on Louisiana last season in a 31-3 victory. The Thundering Herd has momentum right now. While Louisiana is struggling to find the win column. Marshall has too much offensive firepower for Louisiana to keep pace with. Take the road underdog as Marshall is the better team.

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  • Final Score Prediction: Marshall Thundering Herd win 35-20 and cover ATS.

Louisiana vs Marshall Best Free Picks:

  • Marshall Thundering Herd +2.5
  • OVER 46.5

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