Maryland vs Ohio State Picks and Predictions for Saturday October 10 2026

By: Kim Smith Published 10/04/2026, 10:19 PM ET

The Maryland Terrapins visit the No. 5 Ohio State Buckeyes at Ohio Stadium in Columbus, Ohio, on Saturday, October 10, 2026, for a Big Ten matchup. Kickoff is scheduled for 4:15 PM ET. Ohio State enters after an impressive 31-14 road victory over No. 14 Iowa, while Maryland faces a major step up in competition. The current consensus has Ohio State favored by 35.5 points, with the total at 55.5. Be sure to check out our free college football picks for more college football predictions throughout the season.

Maryland Faces Its Toughest Test

Marylandโ€™s challenge begins with finding a way to consistently sustain possessions against one of the best defenses on its schedule. The Terrapins cannot afford repeated three-and-outs because Ohio State has enough offensive ability to turn additional possessions into a large scoring margin.

The biggest concern is what happens if Maryland falls behind early. Ohio State can create pressure when opponents become predictable, and a multiple-score deficit would force the Terrapins away from any balanced offensive approach they want to establish.

The enormous spread does give Maryland considerable room. The Terrapins donโ€™t need to threaten an upset to cover; they simply need to prevent Ohio State from turning the second half into a runaway. At more than five touchdowns, the question becomes less about which team wins and more about whether the Buckeyes remain aggressive long enough to cover.

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Ohio State Continues to Look Elite

Ohio State strengthened its position among the countryโ€™s best teams with a 31-14 road victory over previously unbeaten Iowa. Winning by 17 at Kinnick Stadium against a ranked opponent was another indication that the Buckeyes can dominate without needing perfect offensive conditions.

The defense continues to give Ohio State an enormous margin for error. Iowa entered undefeated and still managed only 14 points, allowing the Buckeyes to control the matchup without needing a massive scoring performance.

That defensive advantage should be even greater against Maryland. The concern from a betting perspective is simply the number. Ohio State could dominate the game, lead comfortably throughout the second half and still struggle to cover 35.5 if the Buckeyes become conservative late.

Maryland vs Ohio State Picks and Predictions

Pick: Maryland +35.5

Maryland +35.5 is the side pick. Ohio State should win comfortably, but more than five touchdowns is an enormous spread for a conference matchup. The Buckeyes just beat a ranked Iowa team 31-14, which was dominant without approaching the margin required here. Maryland can lose decisively and still cash the ticket. Unless Ohio State turns this into a complete blowout before halftime, the Terrapins should have enough points to stay within 35.

Pick: Under 55.5

The Under 55.5 is the stronger play. Ohio Stateโ€™s defense gives Maryland a difficult path toward contributing enough points to push this game Over, while the Buckeyes donโ€™t necessarily need to score into the 40s to control the matchup. A result in the neighborhood of 38-10 or 41-10 would produce a comfortable Ohio State victory while remaining below the number.

Final Picks: Maryland +35.5 and Under 55.5

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