Miami (OH) vs Buffalo Picks and Predictions for Wednesday, November 19, 2025

By: David Anicetti Published 11/16/2025, 03:13 PM ET
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Miami (OH) (5–5, 4–2 MAC) heads to Buffalo (5–5, 4–2 MAC) in a key Mid-American Conference matchup with both teams tied for second in the conference. The RedHawks have dropped two straight after a three-game win streak, while Buffalo has alternated wins and losses over its last four. Build your bankroll with our college football picks.

Miami (OH) vs Buffalo Game Information

Kickoff: 8:00 PM ET, November 19

Where: UB Stadium, Buffalo, NY

TV: ESPN2

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Miami (OH) Outlook

Miami (OH) now turns to senior quarterback Henry Hesson after Dequan Finn left the program to prepare for the NFL. Finn threw for 1,451 yards with nine touchdowns and six interceptions and added 395 rushing yards and four scores before walking away. Hesson has 489 passing yards with three touchdowns and three interceptions this season and went 11-of-38 with three picks in the 24–3 loss to Toledo. The RedHawks are led in rushing by Jordan Brunson, who has 488 rushing yards, while the passing game features big-play threat Kam Perry with 726 receiving yards and four touchdowns.

Defensively, Corban Hondru leads Miami (OH) with 83 tackles and three interceptions, playing a central role both against the run and pass. Adam Trick has 6.5 sacks, giving the front four a pass rusher, and Eli Blakey adds 77 tackles and two interceptions.Β Betting on sports and on Miami (OH)Β  is easy, but even easier if you use the best sportsbooks.

Buffalo Outlook

Buffalo is led by quarterback Ta’Quan Roberson, who has thrown for 1,947 yards with 13 touchdowns and nine interceptions on 59.1% passing. The Bulls get steady production on the ground from Al-Jay Henderson, who has 702 rushing yards and five touchdowns. On the outside, Nik McMillan (712 yards, three touchdowns) and Victor Snow (622 yards, seven touchdowns) give Roberson two primary targets, and Jasaiah Gathings has 359 yards receiving.

Linebacker Red Murdock anchors the Buffalo defense with 114 tackles, while Junior Poyser leads the rush with 5.5 sacks. The Bulls also get pressure from Malin White and George Wolo, and the secondary has created takeaways with Jalen McNair and Solomon Brown combining for three interceptions.Β Make sure you know about how the fans are looking on prediction markets for Buffalo with the social sportsbooks.

Miami (OH) vs Buffalo Prediction

Finn’s departure changes the outlook for Miami (OH), and Hesson is still trying to settle in after a rough outing against Toledo. Buffalo has a more stable situation at quarterback and multiple proven receivers, along with a productive back in Henderson. Buffalo’s passing game and home-field advantage give the Bulls the slight advantage in a matchup that will stay close into the fourth quarter. Final Score Prediction: Buffalo Bulls win and cover ATS, 21–17. Getting the most out of your bets on Miami (OH) vs Buffalo can be done by using the Fanatics Sportsbook promo code.

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