Missouri vs Mississippi State Picks and Predictions for Saturday, September 26th, 2026

Missouri vs Mississippi State Game Information

The Missouri Tigers will be on the road Saturday for the second time this season, facing Mississippi State at Davis Wade Stadium in Starkville, MS, at 7:45 PM. Missouri is ranked No. 19 in the nation and is 3-0 coming into Saturday after a 10-point home win over Troy. The Mississippi State Bulldogs will be back on their home field Saturday, ranked No. 24 in the nation and 3-0 this year after a 7-point road win over South Carolina last week. Keep up with our College Football Picks.

Missouri Preview

Austin Simmons leads Missouri this season with 635 yards and 8 touchdowns on 46 completions without throwing an interception. Matt Zollers has completed 8 passes for 87 yards. Jamal Roberts leads the Tigers with 300 yards and 3 touchdowns on 63 carries. Xai’Shaun Edwards has added 99 yards and 1 score on 20 attempts. Donovan Olugbode leads the receiving corps with 259 yards and 4 touchdowns on 16 catches. Cayden Lee has contributed 239 yards and 2 scores on 15 receptions.

Mississippi State Preview

Kamario Taylor leads Mississippi State this season with 832 yards and 11 touchdowns on 56 completions. Taylor has thrown only 1 interception on 82 attempts, adding 178 yards and 1 score on 27 carries. Fluff Bothwell leads the Bulldogs with 280 yards and 2 touchdowns on 48 attempts. Anthony Evans III leads the receiving attack with 294 yards and 3 scores on 20 catches. Zion Ragins has contributed 159 yards and 3 touchdowns on 8 receptions.

Missouri vs Mississippi State Pick

Both quarterbacks have been extremely efficient, combining for 19 touchdown passes and only 1 interception. Missouri can keep Taylor on the sideline by establishing Roberts, but Mississippi State owns the more explosive offense and has several receivers capable of scoring quickly. Taylor’s mobility should create problems whenever Missouri pressures the quarterback or plays man coverage. The Bulldogs should benefit from home-field advantage and enter with momentum after their victory at South Carolina. Take Mississippi State to win and cover in a high-scoring matchup.

• Pick: Mississippi State Bulldogs -6
• Secondary: Over 59.5

Final Score Prediction: Mississippi State Bulldogs win and cover 35-27.

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