Nebraska vs Michigan State Picks and Predictions for Saturday, September 26th, 2026

By: Cameron Ross Published 09/25/2026, 02:09 PM ET

Nebraska vs Michigan State Game Information

The Nebraska Cornhuskers will be on the road Saturday, facing the Michigan State Spartans at Spartan Stadium in East Lansing, MI, at 5:00 PM. Nebraska is undefeated through its first 3 games this season, following a 27-point victory over North Dakota last week. The Michigan State Spartans return home Saturday, 2-1 this season, following a 17-point road loss to Notre Dame last week. Stay in the news with our College Football Picks.

Nebraska Preview

Anthony Colandrea leads Nebraska this season with 692 yards and 8 touchdowns on 53 completions. Colandrea has thrown only 1 interception through 77 attempts while adding 75 yards and 2 scores on 18 carries. Jamal Rule leads the Cornhuskers with 329 yards and 5 touchdowns on 38 rushing attempts. Mekhi Nelson has contributed 166 yards and 1 score on 27 carries. Jacory Barney Jr. leads the receiving corps with 210 yards and 2 touchdowns on 15 catches.

Michigan State Preview

Alessio Milivojevic leads Michigan State this season with 540 yards and 3 touchdowns on 47 completions. Milivojevic has thrown 2 interceptions through 71 attempts. Cam Edwards leads the Spartans with 288 yards and 3 touchdowns on 60 rushing attempts. Rodney Bullard Jr. leads the receiving attack with 182 yards and 1 touchdown on 12 catches. Jayden Savoury has contributed 129 yards on 11 receptions, while Chrishon McCray has added 84 yards on 11 catches. Charles Taplin has 65 yards and 1 score on 3 catches and Fredrick Moore has added 6 catches for 56 yards and 1 touchdown.

Nebraska vs Michigan State Pick

Michigan State should keep feeding Edwards, but Nebraska’s defense can focus more on stopping the run because the Spartans haven't generated consistent explosive plays through the air. Colandrea gives Nebraska the stronger quarterback play, while Rule has averaged more than 8 yards per carry through the opening 3 games. The Cornhuskers should control possession and gradually create separation during the second half. Take Nebraska to win and cover, with both teams leaning heavily on their rushing attacks and keeping the score under the total.

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  • Pick: Nebraska Cornhuskers -5.5
  • Secondary: Under 48.5

Final Score Prediction: Nebraska Cornhuskers win and cover 27-17.

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